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Clinical reviews
LINKING MASLD AND CVD
Muhammad Shahzeb Khan, MD, MSc; Syed Sarmad Javaid, MBBS; Amreen Dinani, MD; Kara Wegermann, MD; Ambarish Pandey, MD; Ankeet S. Bhatt, MD, MBA, ScM; Mark Muthiah, MBBS; Harriette G.C. Van Spall, MD, MPH; Faiez Zannad, MD, PhD; Javed Butler, MD, MPH, MBA;
·
Cardiology
· 2025
· 24 pages
This document provides a comprehensive overview of metabolic dysfunction-associated steatotic liver disease (MASLD) and its connection to cardiovascular disease, emphasizing the role of cardiologists in managing these conditions.
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Clinical reviews
ECHOCARDIOGRAPHIC EVALUATION OF CARCINOID HEART DISEASE
Mayo Clinic Arizona Cardiovascular Clinical Research Center
·
Cardiology
· 2025
· 19 pages
This article reviews the applications of echocardiography in patients with carcinoid heart disease (CaHD), a complication of metastatic neuroendocrine tumors. It discusses the diagnostic imaging techniques used for identification and management of CaHD.
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Clinical reviews
RETROPERITONEUM AND PELVIC EXTRAPERITONEUM: ANATOMIC LANDMARKS, IMAGING FEATURES, AND PATTERNS OF DISEASE SPREAD
Ayman H. Gaballah, MD; Maged Algazzar, MD; Irfan A. Kazi, MD; Mohamed Badawy, MD; Muhammad Awiwi, MD; Amr Shabana, MD; Mindy Wang, MD; Akram Shabaan, MD; Moataz Soliman, MD; Khaled M. Elsayes, MD; Yashant Aswani, MD; Peter S. Liu, MD; Jennifer Sammon, MD
·
Radiology
· 22 pages
This document discusses the complex anatomical spaces of the retroperitoneum and pelvic extraperitoneum, highlighting their vital structures and the patterns of disease spread within these regions. It emphasizes the importance of imaging modalities such as CT and MRI in identifying normal anatomy and characterizing pathological processes.
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Clinical reviews
ENCEPHALITIS
Nuffield Department of Clinical Neurosciences, University of Oxford; Department of Neurology, John Radcliffe Hospital; Department of Neurology, University of North Carolina; Encephalitis International; Department of Clinical Infection, Microbiology and
·
Neurology
· 2026
· 16 pages
This document discusses the urgent global emergency of brain inflammation due to encephalitis, highlighting clinical approaches to recognize and distinguish common pathogenic viruses and emerging autoantibodies. It emphasizes the importance of timely investigations and treatment strategies.
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Clinical reviews
INTERNATIONAL ANALGESIA AND SEDATION WEANING AND WITHDRAWAL PRACTICES IN CRITICALLY ILL ADULTS: THE ADULT IATROGENIC WITHDRAWAL STUDY IN THE ICU
Dr. Bolesta
·
Critical Care Medicine
· 2023
· 13 pages
This study aimed to determine the prevalence, utilization, and characteristics of opioid and sedative weaning and iatrogenic withdrawal syndrome (IWS) policies in the adult ICU population.
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Clinical reviews
INTRACEREBRAL HAEMORRHAGE
Lille Neuroscience & Cognition (LilNCog), University of Lille, Inserm, CHU Lille, France; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust & University of Manchester, UK
·
Neurology
· 2023
· 18 pages
Intracerebral haemorrhage (ICH) is a dramatic condition caused by the rupture of a cerebral vessel and the entry of blood into the brain parenchyma. It is a major contributor to stroke-related mortality and dependency.
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Clinical reviews
NEW CONCEPT PRESENTATION
Busitema University
·
Pharmacology
· 2026
· 18 pages
A student research project assessing the mutagenic and teratogenic potential of the GLUKOTAK poly‑herbal formulation using in‑vitro Ames test and in‑vivo rat studies.
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Clinical reviews
METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS
Joshua B. Parsons, Annette C. Westgeest, Brian P. Conlon, Stephan Harbarth, Benjamin P. Howden, Yang Soo Kim, Heather A. King, Merel M. C. Lambregts, Loren G. Miller, Robin Patel, Minggui Wang, Vance G. Fowler Jr
·
Infectious Diseases
· 23 pages
This document discusses Methicillin-resistant Staphylococcus aureus (MRSA), a significant cause of antimicrobial-resistant infections, detailing its epidemiology, pathogenesis, and clinical management strategies.
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Clinical reviews
HEPARIN-INDUCED THROMBOCYTOPAENIA
Federal University of Rio de Janeiro, Seha Kidney Care, Imperial College Healthcare NHS Trust
·
Critical Care Medicine
· 6 pages
This document discusses the pathophysiology, incidence, and management of heparin-induced thrombocytopaenia (HIT), an immune complication arising from heparin therapy.
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Clinical reviews
SURGICAL SITE INFECTIONS AFTER CESAREAN DELIVERY
Misa Hayasaka, MD; Helain J. Landy, MD; Lauren Forbes, MD, MPH; Abigail Barger, MD; Salimah Navaz Gangii, MD; George Saade, MD; Tetsuya Kawakita, MD, MS
·
Obstetrics and Gynecology
· 17 pages
This document provides a comprehensive overview of surgical site infections (SSIs) following cesarean delivery, including definitions, risk factors, microbiology, clinical presentation, evaluation, prevention strategies, and management.
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Clinical reviews
AUTOIMMUNE HEPATITIS
null
·
Hepatology
· 2018
· 22 pages
Autoimmune hepatitis (AIH) is a severe liver disease that affects children and adults worldwide, characterized by a T cell-mediated autoimmune response against liver autoantigens. The disease responds favorably to immunosuppressive treatment, which should be initiated promptly upon diagnosis.
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Clinical reviews
CARDIOVASCULAR COMPLICATIONS IN CHRONIC KIDNEY DISEASE: A REVIEW FROM THE EUROPEAN RENAL AND CARDIOVASCULAR MEDICINE WORKING GROUP OF THE EUROPEAN RENAL ASSOCIATION
Various institutions including Renal Research Institute, Grande Ospedale Metropolitano, Medical University of Silesia, University of Campinas, and others
·
Nephrology
· 16 pages
This document reviews the cardiovascular complications associated with chronic kidney disease (CKD), highlighting the interplay between renal and cardiovascular health. It discusses recent findings and recommendations for managing these complications.
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Clinical reviews
CONTEMPORARY DIAGNOSIS AND TREATMENT OF AORTIC REGURGITATION
American College of Cardiology Foundation
·
Cardiology
· 2026
· 29 pages
This state-of-the-art review discusses the progressive nature of aortic regurgitation (AR) and the advancements in imaging techniques that enable earlier detection and treatment. It highlights the importance of timely intervention to prevent adverse left-ventricular remodeling and heart failure.
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Clinical reviews
ARRHYTHMIC SYNCOPE: FROM DIAGNOSIS TO MANAGEMENT
Hospital Universitari Vall d'Hebron, Barcelona, Spain
·
Cardiology
· 2023
· 24 pages
This review discusses the complexities of arrhythmic syncope, including its diagnosis and management strategies. It highlights the importance of identifying underlying pathologies that may lead to syncope, ranging from benign to life-threatening conditions.
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Clinical reviews
STATE-OF-THE-ART REVIEW
Department of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano; Department of Cardiology, National Heart Foundation Hospital and
·
Cardiology
· 16 pages
This state-of-the-art review summarizes the contemporary clinical management of myocardial infarction (MI), highlighting advancements in acute and long-term care, including timely revascularization and secondary prevention measures.
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Clinical reviews
PHARMACOLOGICAL MANAGEMENT OF OBSTETRIC HAEMORRHAGE: AN EVIDENCE-BASED APPROACH
Faculty of Medicine, Universidad Autónoma de Queretaro, Queretaro, Mexico
·
Obstetrics and Gynecology
· 8 pages
This document provides an evidence-based approach to the pharmacological management of obstetric haemorrhage, focusing on the use of uterotonics and tranexamic acid for effective treatment.
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Clinical reviews
Tryps Year2 2018 19
Infectious Diseases
· 27 pages
A concise overview of Trypanosoma species, including African trypanosomiasis and Trypanosoma cruzi, their vectors, clinical manifestations, laboratory diagnosis, and treatment considerations.
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Clinical reviews
ACUTE AORTIC DISSECTION
Thierry Carrel, Thoralf M Sundt 3rd, Yskert von Kodolitsch, Martin Czerny
·
Cardiovascular Surgery
· 2023
· 16 pages
This document provides a clinically relevant overview of the prevention, diagnosis, and management of acute aortic dissection, a complex cardiovascular event with high mortality and morbidity.
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Clinical reviews
SUPPLEMENTARY APPENDIX
Dr. Frank Post
·
Infectious Disease
· 151 pages
This supplementary appendix includes additional data and figures related to the RIO trial, which investigates the time to HIV rebound after infusion of long-acting broadly neutralising antibodies.
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Clinical reviews
50 STUDIES EVERY DOCTOR SHOULD KNOW
University of California, Los Angeles
·
General Medicine
· 2014
· 247 pages
This document presents key studies that form the foundation of evidence-based medicine, providing insights into various clinical practices and their outcomes.
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Clinical reviews
MASLD, MASH, and the CKM Spectrum: A Roadmap for Multiorgan Clinical Trial Design
American College of Cardiology Foundation
·
Cardiology
· 2026
· 28 pages
This document reviews the interconnections between cardiovascular, kidney, and metabolic diseases alongside liver disease, emphasizing the need for integrated clinical trial designs that address these comorbidities.
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Clinical reviews
ASTHMA IN PREGNANCY: CONTEMPORARY MANAGEMENT
Icahn School of Medicine at Mount Sinai, The Ohio State University Wexner Medical Center, University of Nebraska Medical Center, Duke University School of Medicine
·
Obstetrics and Gynecology
· 23 pages
This document discusses the management of asthma during pregnancy, highlighting the risks associated with uncontrolled asthma and the importance of maintaining control through appropriate therapy.
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Clinical reviews
DELIRIUM IN CARDIOVASCULAR MEDICINE
Universitätsklinikum Bonn, University Hospital Bonn, TU Dresden, University Heart and Vascular Center Hamburg, Vall d’Hebron Hospital Universitari, Antwerp University Hospital, AO SS Antonio e Biagio e Cesare Arrigo
·
Cardiology
· 2026
· 24 pages
This state-of-the-art review discusses the incidence, prevention, and treatment of delirium in patients with cardiovascular conditions, highlighting the importance of multidisciplinary approaches.
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Clinical reviews
TRICUSPID REGURGITATION
Columbia University Irving Medical Center, New York–Presbyterian Hospital
·
Cardiology
· 2023
· 16 pages
This review article discusses the complexities of diagnosing and managing tricuspid regurgitation, a condition often overlooked in clinical practice. It highlights the importance of early diagnosis and the implications of severe tricuspid regurgitation on patient outcomes.
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