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Kevin Damman, MD, PhD; Dirk J. van Veldhuisen, MD, PhD; Johann Bauersachs, MD; Michiel Rienstra, MD, PhD; Arend Mosterd, MD, PhD; Adriaan A. Voors, MD, PhD; Geert H. D. Voordes, MD; Udo Bavendiek, MD; Peter van der Meer, MD, PhD
The study investigates the role of digitalis glycosides as an additional therapy for heart failure patients, focusing on their impact on cardiovascular death and worsening heart failure events. A systematic review of the literature identified three major trials involving over 9000 patients, providing insights into the effectiveness and safety of these medications. The analysis adheres to rigorous methodological standards, including risk of bias assessment and statistical evaluation of outcomes.
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