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Clinical reviews
ADVANCES IN CONGESTION ASSESSMENT IN DECOMPENSATED HEART FAILURE
Essex Cardiothoracic Centre, Mid and South Essex NHS Foundation Trust; Anglia Ruskin University School of Medicine and Medical Technical Research Centre
·
Cardiology
· 2026
· 10 pages
This review explores traditional and emerging methods for evaluating congestion in acute decompensated heart failure (ADHF) and assesses their role in enhancing clinical management. Accurate assessment of congestion is crucial for guiding diuretic treatment and preventing rehospitalisation.
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Clinical reviews
ASSESSING CONGESTION IN HEART FAILURE: TOOLS ARE ALREADY AVAILABLE, BUT INTEGRATION IS KEY
INSERM UMR-S 942, Université de Paris Cité, Paris, France
·
Cardiology
· 2026
· 14 pages
This review summarizes current and emerging approaches for evaluating congestion in heart failure, emphasizing the need for integration of clinical, imaging, hemodynamic, and patient-centered strategies for optimal management.
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Clinical reviews
PHARMACOTHERAPY OF HEART FAILURE A.D. 2023
Medical University of Lodz, Collegium Medicum Jan Kochanowski University, Maria Skłodowska-Curie Medical Academy, Medical University of Warsaw, Świętokrzyskie Cardiology Center
·
Cardiology
· 2023
· 20 pages
This document provides expert opinions on the pharmacotherapy of heart failure, focusing on recent advancements and recommendations in treatment strategies.
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Clinical reviews
ASPIRIN WITH OR WITHOUT STATIN IN INDIVIDUALS WITHOUT ATHEROSCLEROTIC CARDIOVASCULAR DISEASE ACROSS RISK CATEGORIES
American College of Cardiology Foundation
·
Cardiology
· 2023
· 12 pages
This study examines the effects of aspirin in adults without atherosclerotic cardiovascular disease, stratified by statin use across different ASCVD risks.
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Clinical reviews
EASY-WPW: a novel ECG-algorithm for easy and reliable localization of manifest accessory pathways in children and adults
Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Georgstr. 11, 32545 Bad Oeynhausen, Germany
·
Cardiology
· 2022
· 10 pages
This clinical research paper introduces the EASY-WPW algorithm, a new electrocardiogram (ECG) based method designed for the accurate and straightforward localization of accessory pathways in both pediatric and adult patients. The study evaluates its performance against existing algorithms.
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Clinical notes
ACUTE CORONARY SYNDROMES
Dr. Daniel Iraguha
·
Cardiology
· 42 pages
This document discusses acute coronary syndromes (ACS), including STEMI, NSTEMI, and unstable angina, highlighting their global impact, incidence, and management strategies.
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Clinical reviews
ANTIARRHYTHMIC DRUG THERAPY FOR ACUTE MANAGEMENT OF ATRIAL FIBRILLATION AND ATRIAL FLUTTER
Mohammadali Habibi, MD; Muhammed Rahim, MD; Suneet Mittal, MD
·
Cardiology
· 9 pages
This document discusses the management of acute atrial fibrillation (AF) and atrial flutter (AFL) through antiarrhythmic drug therapy, emphasizing the importance of rate and rhythm control.
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Clinical reviews
VALVULAR HEART FAILURE DUE TO TRICUSPID REGURGITATION SURGICAL AND TRANSCATHETER MANAGEMENT OPTIONS
Columbia University
·
Cardiology
· 15 pages
This document discusses the surgical and transcatheter management options for valvular heart failure due to tricuspid regurgitation, highlighting the importance of understanding the condition's etiology and treatment strategies.
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Clinical reviews
WITHDRAWAL OF PHARMACOLOGICAL TREATMENT FOR HEART FAILURE IN PATIENTS WITH RECOVERED DILATED CARDIOMYOPATHY (TRED-HF): AN OPEN-LABEL, PILOT, RANDOMISED TRIAL
Royal Brompton and Harefield NHS Foundation Trust, London, UK
·
Cardiology
· 13 pages
This document presents a pilot randomized trial examining the safety and effects of withdrawing heart failure medications in patients with recovered dilated cardiomyopathy.
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Clinical reviews
CARDIAC TUMORS: DIAGNOSIS, PROGNOSIS, AND TREATMENT
Rossana Bussani, Matteo Castrichini, Luca Restivo, Enrico Fabris, Aldostefano Porcari, Federico Ferro, Alberto Pivetta, Renata Korcova, Chiara Cappelletto, Paolo Manca, Vincenzo Nuzzi, Riccardo Bessi, Linda Pagura, Laura Massa, Gianfranco Sinagra
·
Cardiology
· 2020
· 13 pages
This document provides an overview of cardiac tumors, discussing their epidemiology, imaging, histopathology, diagnostic workup, treatment, and prognoses. It highlights the challenges in diagnosing and managing these rare tumors.
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Clinical reviews
WORSENING OF CHRONIC HEART FAILURE: DEFINITION, EPIDEMIOLOGY, MANAGEMENT AND PREVENTION. A CLINICAL CONSENSUS STATEMENT BY THE HEART FAILURE ASSOCIATION (HFA) OF THE ESC
Heart Failure Association of the European Society of Cardiology
·
Cardiology
· 2023
· 39 pages
This document provides a comprehensive consensus statement on the definition, epidemiology, management, and prevention of worsening chronic heart failure, developed by the Heart Failure Association of the European Society of Cardiology.
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Clinical reviews
ACUTE MITRAL REGURGITATION
Miyazaki Medical Association Hospital Cardiovascular Center
·
Cardiology
· 2019
· 7 pages
This document discusses the diagnosis and management of acute mitral regurgitation (MR), highlighting the differences from chronic MR and the challenges in treatment based on various aetiologies.
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Clinical reviews
THROMBOTIC AND BLEEDING COMPLICATIONS DURING ANTITHROMBOTIC TREATMENT: THE NEED FOR NEW THERAPEUTIC TARGETS
Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy
·
Cardiology
· 4 pages
This document discusses the significant advancements in pharmacological management for cardiovascular disease patients using antithrombotic agents, while highlighting the persistent risks of bleeding complications.
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Clinical reviews
HEART FAILURE WITH IMPROVED EJECTION FRACTION
American College of Cardiology Foundation
·
Cardiology
· 2025
· 15 pages
This document provides an in-depth evaluation of heart failure with improved ejection fraction (HFimpEF), including its epidemiology, pathophysiology, prognosis, and treatment strategies.
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Clinical reviews
Management of Cardiogenic Shock in Patients with Acute Myocardial Infarction
Katherine J. Kunkel, MD, MSEd, Brittany Fuller, MD, Mir B. Basir, DO
·
Cardiology
· 13 pages
This document discusses the management strategies for cardiogenic shock in patients experiencing acute myocardial infarction, emphasizing the importance of early identification and mechanical support.
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Clinical reviews
SYSTEMATIC REVIEW AND META-ANALYSIS OF DIAGNOSTIC TEST ACCURACY OF ST-SEGMENT ELEVATION FOR ACUTE CORONARY OCCLUSION
Instituto Dante Pazzanese de Cardiologia, São Paulo, Brazil
·
Cardiology
· 2021
· 7 pages
This systematic review evaluates the diagnostic sensitivity and specificity of ST-segment elevation on a 12-lead ECG in detecting acute coronary occlusion (ACO). It challenges the current STEMI-NSTEMI paradigm by analyzing data from multiple studies.
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Clinical reviews
BEYOND THE 4 PILLARS
Città della Salute e della Scienza Hospital, Turin, Italy
·
Cardiology
· 4 pages
This editorial comment discusses the role of vericiguat in the management of heart failure with reduced ejection fraction (HFrEF), emphasizing its potential benefits and the challenges in treatment outcomes.
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Clinical reviews
ALDOSTERONE SYNTHASE INHIBITORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE
Gian Paolo Rossi, Federico Bernardo Rossi, Andrea Cignarella, Teresa Maria Seccia
·
Cardiology
· 2026
· 11 pages
This review discusses the role of aldosterone synthase inhibitors (ASIs) in managing cardiovascular diseases, particularly focusing on their efficacy in lowering aldosterone levels and blood pressure in patients with resistant hypertension.
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Clinical reviews
TIME TO MOVE BEYOND THE STATIN NOCEBO EFFECT
Yale School of Medicine
·
Cardiology
· 3 pages
This editorial discusses the challenges associated with statin therapy, particularly the nocebo effect that leads many patients to discontinue their medication despite its proven benefits in cardiovascular prevention.
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Clinical reviews
FEMORAL VEIN PULSATILITY: A SIMPLE TOOL FOR VENOUS CONGESTION ASSESSMENT
V. Bhardwaj, P. Rola, A. Denault, G. Vikneswaran, R. Spiegel
·
Cardiology
· 10 pages
This article discusses the use of femoral vein Doppler (FVD) as a simpler alternative to the VExUS score for assessing venous congestion in adult post-cardiac surgery patients.
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Clinical reviews
SAFETY, TOLERABILITY, AND EFFICACY OF UP-TITRATION OF GUIDELINE-DIRECTED MEDICAL THERAPIES FOR ACUTE HEART FAILURE (STRONG-HF): A MULTINATIONAL, OPEN-LABEL, RANDOMISED, TRIAL
Université Paris Cité, INSERM UMR-S 942 (MASCOT), Paris, France
·
Cardiology
· 2022
· 15 pages
This document presents the findings of a multinational trial assessing the safety, tolerability, and efficacy of up-titration of guideline-directed medical therapies in patients with acute heart failure.
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Clinical reviews
CURRENT CONCEPTS IN CORONARY ARTERY REVASCULARISATION
Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA; Department of Cardiovascular, Policlinico Universitario Gemelli IRCCS, Rome, Italy; Osaka Hospital, Osaka, Japan
·
Cardiology
· 2023
· 18 pages
This document discusses the methods of coronary artery revascularisation, including surgical and percutaneous approaches, highlighting their respective risks and benefits. It emphasizes the importance of medical therapy in conjunction with revascularisation.
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Clinical reviews
THE ROLE OF β-BLOCKERS IN THE EVOLVING TREATMENT LANDSCAPE OF RESISTANT HYPERTENSION
Stefano Masi, Atul Pathak, Rosa Maria Bruno, Sofie Brouwers, Krzysztof Narkiewicz, Stefano Taddei, Konstantinos Tsioufis, Reinhold Kreutz
·
Cardiology
· 2026
· 21 pages
This narrative review summarizes mechanistic insights and evidence from clinical trials and real-world studies regarding the management of resistant hypertension (RHTN), focusing on the role of β-blockers.
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Guidelines & protocols
EXPERTS' RECOMMENDATIONS FOR THE MANAGEMENT OF ADULT PATIENTS WITH CARDIOGENIC SHOCK
Hôpital Européen Georges Pompidou, Toulouse University Hospital, University Hospital of Strasbourg, and others
·
Cardiology
· 19 pages
This document provides expert recommendations for the management of adult patients experiencing cardiogenic shock, focusing on various treatment modalities and their outcomes.
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