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Clinical reviews
Kidney disease and heart failure
Carolyn S.P. Biykem Bozkurt, David Z.I. Cherney, Justin A. Ezekowitz, Meg J. Jardine, Sadiya S. Khan, Magdalena Madero, Mark J. Sarnak, Jozine M. ter Maaten, Michael Cheung, Jennifer M. King, Morgan E. Grams, Michel Jadoul, Nisha Bansal
PDF202419 pages2.7 MB
The document synthesizes recent advances presented at the KDIGO Controversies Conference, highlighting the impact of SGLT2 inhibitors, diuretic strategies, and sodium restriction on renal and cardiac outcomes. It discusses the role of biomarkers such as NT‑proBNP and the importance of exercise and quality‑of‑life measures. Controversies surrounding acute GFR declines, optimal decongestion targets, and patient‑reported outcomes are examined. The review calls for large‑scale trials to clarify optimal therapies for the cardiorenal population.
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