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Clinical reviews
RECENT TOPICS AND ADVANCED THERAPIES IN CHRONIC GRANULOMATOUS DISEASE
Japan Human Cell Society
PDF202213 pages1.5 MB
Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by the inability of phagocytes to produce reactive oxygen species (ROS), leading to increased risk of life-threatening infections and inflammatory complications. The document discusses advancements in antimicrobial prophylaxis and immunomodulatory treatments, as well as the role of gene therapy in treating CGD. It highlights the importance of understanding ROS in innate immunity and its implications for patient management.
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