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Clinical reviews
MECHANISMS OF RESISTANCE TO NEWER DRUGS AGAINST GRAM
Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen Macarena/CSIC/Universidad Sevilla, Spain
PDF20267 pages864 KB
The emergence of antibiotic resistance in Gram-negative bacteria poses a significant challenge to global health. This has prompted the development of novel antimicrobials and combinations with β-lactamase inhibitors. The review discusses various resistance mechanisms, particularly focusing on newer drugs and their efficacy against resistant strains. It synthesizes findings from recent literature to provide insights into the molecular underpinnings of resistance.
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