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Clinical reviews
IDIOPATHIC INFLAMMATORY MYOPATHIES
Ingrid E. Lundberg, Manabu Fujimoto, Jiri Vencovsky, Rohit Aggarwal, Marie Holmqvist, Lisa Christopher-Stine, Andrew L. Mammen, Frederick W. Miller
PDF202122 pages3.7 MB
Idiopathic inflammatory myopathies (IIM) are systemic inflammatory disorders that present with muscle weakness and can affect various organs, including the skin, joints, and lungs. The document classifies IIM into several subgroups based on clinical, histopathological, and serological features, such as dermatomyositis and polymyositis. It emphasizes the importance of understanding the molecular pathways and auto-antigens involved in these disorders to improve patient outcomes and guide treatment decisions. The document also highlights the need for targeted therapies and biomarkers for better management of IIM.
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