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First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, Yunnan, China; Joint Graduate School of Traditional Chinese Medicine of China, Suzhou, China
The document provides a comprehensive review of the multifactorial aspects contributing to the pathogenesis of rheumatoid arthritis. It highlights the role of immune dysregulation, metabolic changes, and mechanical factors in the disease's progression. The authors discuss the implications of these findings for therapeutic strategies targeting mechanobiological processes. The review aims to clarify the complex interactions between these factors and their contributions to RA.
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