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Clinical reviews
HIV Associated Cancers and related diseases (2)
National Cancer Institute, Center for Cancer Research, Bethesda, MD
PDF201813 pages1.5 MB
The article outlines the epidemiology and pathogenesis of HIV‑associated cancers, highlighting the historical rise of Kaposi’s sarcoma, aggressive B‑cell lymphomas, and invasive cervical cancer as AIDS‑defining conditions. It discusses the impact of antiretroviral therapy on cancer incidence and survival, and reviews treatment strategies for both AIDS‑defining and non‑AIDS‑defining malignancies, including the use of rituximab and standard chemotherapy regimens. The review also addresses emerging cancers in the HIV population and considerations for clinical trial eligibility, emphasizing the need for tailored management in this immunocompromised group.
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