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Clinical reviews
Intubation in the Critically Ill: When, How, and How Long?
Luis Ng, Shubhang K. Bhatt, Benjamin R. Stultz, Gustavo A. Cortes-Puentes
·
Critical Care Medicine
· 16 pages
This article discusses endotracheal intubation, a crucial procedure for managing critically ill patients, covering its indications, techniques, and post-intubation management. It emphasizes the importance of clinician judgment, physiological parameters, and team preparation for successful outcomes.
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Clinical reviews
MYOCARDIAL BRIDGING: A PRACTICAL GUIDE FOR CLINICIANS
Baylor College of Medicine, Karolinska Institutet, Emory University, University of Eastern Piedmont, Houston Methodist Hospital, Cedars-Sinai Medical Center, Azienda Ospedaliero-Universitaria Maggiore Della Carità, Mayo Clinic
·
Cardiology
· 13 pages
This document provides a comprehensive overview of myocardial bridging, including its mechanisms, diagnostic approaches, and management strategies for clinicians.
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Clinical reviews
A Contemporary Approach to the Diagnosis and Management of Constrictive Pericarditis
Division of Cardiology, McGill University Health Centre; Department of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University; Division of Cardiology, Jewish General Hospital
·
Cardiology
· 2023
· 13 pages
This document provides a comprehensive overview of the diagnosis and management strategies for constrictive pericarditis, focusing on advanced imaging techniques and treatment options.
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Clinical reviews
MYELODYSPLASTIC SYNDROMES: 2023 UPDATE ON DIAGNOSIS, RISK-STRATIFICATION, AND MANAGEMENT
University of Texas MD Anderson Cancer Center
·
Hematology
· 2023
· 19 pages
This document provides an update on the diagnosis, risk-stratification, and management of myelodysplastic syndromes (MDS), a heterogeneous group of myeloid disorders. It discusses the new WHO classification, diagnostic criteria, and risk-adapted therapy options.
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Clinical reviews
MANAGEMENT OF MECHANICAL PROSTHETIC HEART VALVE THROMBOSIS
Journal of the American College of Cardiology
·
Cardiology
· 2023
· 13 pages
This document discusses the complications associated with mechanical prosthetic heart valves, particularly focusing on mechanical valve thrombosis (MVT) and its management strategies.
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Clinical reviews
STATE - OF - THE - ART REVIEW: ß - BLOCKADE IN CRITICAL ILLNESS
Marlies Ostermann, Daniel De Backer, Emilie Belley‑Cote, Maurizio Cecconi, Michelle S. Chew, Joanna C. Dionne, Steven M. Hollenberg, Stephan M. Jakob, Salmaan Kanji, Richard Leach, Mark J. McPhail, Xavier Monnet, Andrea Morelli, Mervyn Singer, Erika
·
Critical Care Medicine
· 2026
· 18 pages
This narrative review evaluates the role of ß-blocker therapy as a potential strategy to modulate or counteract the adrenergic response in critically ill patients. It discusses the context-dependent benefits and controversies surrounding their use.
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Clinical reviews
STATE - OF - THE - ART REVIEW: ß - BLOCKADE IN CRITICAL ILLNESS
Marlies Ostermann, Daniel De Backer, Emilie Belley‑Cote, Maurizio Cecconi, Michelle S. Chew, Joanna C. Dionne, Steven M. Hollenberg, Stephan M. Jakob, Salmaan Kanji, Richard Leach, Mark J. McPhail, Xavier Monnet, Andrea Morelli, Mervyn Singer, Erika
·
Critical Care Medicine
· 2026
· 18 pages
This state-of-the-art review evaluates the role of ß-blocker therapy as a potential strategy to modulate or counteract the adrenergic response in critically ill patients. It discusses the context-dependent benefits and controversies surrounding their use.
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Clinical reviews
GLIFLOZINS IN THE MANAGEMENT OF CARDIOVASCULAR DISEASE
Brigham and Women’s Hospital, Harvard Medical School
·
Cardiology
· 2022
· 11 pages
This review article discusses the role of SGLT2 inhibitors, commonly known as gliflozins, in managing cardiovascular disease, particularly in patients with type 2 diabetes.
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Clinical reviews
CONDUCTION DISTURBANCES AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION
The Heart Centre, Rigshospitalet, Copenhagen, Denmark; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Quebec City, Canada; Institut
·
Cardiology
· 2026
· 23 pages
This document reviews the incidence, risk factors, and management of conduction disturbances following transcatheter aortic valve implantation (TAVI). It discusses the implications for patient monitoring and potential need for permanent pacemaker implantation.
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Clinical reviews
ATRIAL TACHYCARDIA: A NOVEL CLASSIFICATION AND CONTEMPORARY MANAGEMENT
American College of Cardiology Foundation
·
Cardiology
· 2026
· 11 pages
This state-of-the-art review discusses the evolution of atrial tachycardia (AT) management, highlighting recent advances in mechanistic understanding and therapeutic strategies.
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Clinical reviews
PERIPHERAL T-CELL LYMPHOMAS
Lausanne University Hospital, Hôpitaux Universitaires Henri Mondor, Memorial Sloan Kettering Cancer Center
·
Hematology
· 18 pages
This document provides a practical approach to the modern diagnosis and classification of T- and NK-cell lymphomas, focusing on their biological and clinical diversity.
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Clinical reviews
MANAGEMENT OF POSTPARTUM HYPERTENSIVE DISORDERS OF PREGNANCY
Brown Evidence-based Practice Center
·
Obstetrics and Gynecology
· 2023
· 215 pages
This systematic review and meta-analysis evaluates the management of postpartum hypertensive disorders of pregnancy, providing evidence-based recommendations.
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Clinical reviews
ACUTE MYOCARDIAL INFARCTION IN PREGNANCY: A MULTIDISCIPLINARY APPROACH
Hamad Medical Corporation, Doha, QAT; College of Medicine, Qatar University, Doha, QAT
·
Cardiology
· 2026
· 22 pages
This review article discusses the increased hemodynamic demands on the cardiovascular system during pregnancy and the implications of acute myocardial infarction (AMI) in pregnant women, including diagnosis and treatment.
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Clinical reviews
ANTI-OBESITY DRUGS: COMPREHENSIVE REVIEW AND EMERGING THERAPIES
Pranav Marne, Swapnil Patil, Amisha Vora, Mohd Usman Mohd Siddiqui, Yatin Gadkari, Prashant Kurkute
·
Endocrinology
· 2026
· 26 pages
This review article evaluates the status of presently approved anti-obesity medications and novel therapeutic candidates under clinical investigation, focusing on their mechanisms of action, efficacy, safety profiles, and therapeutic potential.
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Clinical reviews
DRUG DELIVERY SYSTEMS FOR THYROID DISEASE TREATMENT: A MINI REVIEW ON CURRENT THERAPIES AND ALTERNATIVE APPROACHES
School of Pharmacy, Queen’s University Belfast; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Universidad de Sevilla; Pharmacy Department, Belfast City Hospital; Department of Pharmaceutical Engineering, Azrieli College of
·
Endocrinology
· 12 pages
This review article discusses various drug delivery systems for the treatment of thyroid diseases, focusing on current therapies and alternative approaches. It highlights the importance of thyroid hormones in metabolic processes and the therapeutic management of hypothyroidism and hyperthyroidism.
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Clinical reviews
UPDATE ON CUTANEOUS LUPUS ERYTHEMATOSUS PATHOGENESIS, DIAGNOSIS AND MANAGEMENT
Faculty of Medicine, Tenon Hospital, Sorbonne University, Paris, France
·
Dermatology
· 2025
· 19 pages
This review provides an updated synthesis of current knowledge on cutaneous lupus erythematosus (CLE), including its classification, pathogenesis, clinical presentation, and diagnostic strategy.
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Clinical reviews
PLEURAL EFFUSION IN CRITICALLY ILL PATIENTS AND INTENSIVE CARE SETTING
Dr. Sulaiman Al Habib Medical Group
·
Pulmonology
· 2023
· 12 pages
This minireview discusses the diagnosis and management of pleural effusion in critically ill patients, emphasizing the role of ultrasound as a diagnostic tool in the intensive care unit (ICU).
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Clinical reviews
USE OF HYPERTONIC SALINE IN NEUROANESTHESIA AND NEUROCRITICAL CARE PRACTICE: A NARRATIVE REVIEW
Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India
·
Neuroanesthesia
· 2023
· 9 pages
This narrative review evaluates the use of hypertonic saline (HTS) in neuroanesthesia and neurocritical care, focusing on its mechanisms and clinical applications.
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Clinical reviews
SEXUAL AND REPRODUCTIVE HEALTH AND RIGHTS
Dr. Jolly K. Beyeza
·
Public Health
· 49 pages
This document discusses the importance of sexual and reproductive health and rights (SRHR) as essential components of universal health coverage, focusing on definitions, global and local situations, and the impact of the COVID-19 pandemic.
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Clinical reviews
OTHER BENEFITS OF CONTROLLING CARBOHYDRATES
Brigham Young University
·
Endocrinology
· 279 pages
This document explores the impact of carbohydrate control on health, particularly focusing on insulin resistance as a root cause of various chronic diseases.
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Clinical reviews
EXTERNAL VENTRICULAR DRAINAGE: A PRACTICAL GUIDE FOR NEURO-ANESTHESIOLOGISTS
Department of Neurosurgery, AON SS. Antonio e Biagio e Cesare Arrigo University Hospital; Department of Neurosurgery, IRCCS S. Matteo University Hospital, University of Pavia; Department of Anesthesiology and Perioperative Medicine, University of
·
Neuroanesthesiology
· 11 pages
This document provides a comprehensive review of external ventricular drainage (EVD), focusing on its management in neurocritical care, particularly for patients with subarachnoid hemorrhage and severe traumatic brain injury.
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Clinical reviews
RECENT ADVANCES IN THE TREATMENT OF MALARIA
King Saud University, Al-Imam Mohammad Ibn Saud Islamic University, King Faisal Specialist Hospital & Research Center, Alfaisal University
·
Infectious Disease
· 23 pages
This review provides a comprehensive overview of recent developments in malaria treatment, focusing on the evolution of drug therapies, mechanisms of action, and emerging resistance patterns.
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Clinical reviews
DEFINING SEPSIS PAST, PRESENT, AND FUTURE
Elizabeth S. Munroe, MD, MSc, Hallie C. Prescott, MD, MSc
·
Infectious Disease
· 15 pages
This document discusses the definition of sepsis, its historical context, and the challenges in establishing a common understanding for clinical practice and research. It emphasizes the importance of a shared definition for improving management and treatment outcomes.
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Clinical reviews
THE DIAGNOSIS AND MANAGEMENT OF EXTRAUTERINE AND UTERINE ECTOPIC PREGNANCY
University College London Hospitals NHS Foundation Trust, University College London, Anglia Ruskin University
·
Obstetrics and Gynecology
· 2025
· 32 pages
This document provides a comprehensive overview of the diagnosis and management of ectopic pregnancies, including risk factors, clinical evaluation, and treatment options.
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