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Resources
24 shown
Clinical reviews
ALBUMIN USE IN CIRRHOSIS
University of Münster, European Foundation for Study of Chronic Liver Failure, University of Southern Denmark, Yale University, VA-CT Healthcare System
·
Gastroenterology
· 2025
· 16 pages
This document discusses the controversies surrounding the use of albumin therapy in patients with cirrhosis, focusing on its benefits and the complexities of its administration.
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Medicines & prescribing
VALPROATE (VALPROIC ACID): DRUG INFORMATION
UpToDate, Inc.
·
Neurology
· 2026
· 110 pages
This document provides comprehensive drug information on valproate (valproic acid), including its uses, risks, and monitoring requirements.
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Guidelines & protocols
CANADIAN ADULT OBESITY CLINICAL PRACTICE GUIDELINE: PHARMACOTHERAPY FOR OBESITY MANAGEMENT IN ADULTS
University of Calgary, University of British Columbia, University of Toronto, McMaster University, Obesity Canada
·
Endocrinology
· 2025
· 26 pages
This document provides updated clinical practice guidelines for the pharmacotherapy of obesity management in adults, emphasizing the importance of health parameter improvement over mere weight reduction.
1
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Clinical reviews
PATIENT SELF-INFLICTED LUNG INJURY AN IMPORTANT PHENOMENON
Eleonora Balzani, Glasiele C. Alcala, Giacomo Bellani, Antonio Pesenti
·
Pulmonology
· 8 pages
This review summarizes mechanistic insights, preclinical and clinical evidence, and current strategies to prevent patient self-inflicted lung injury (P-SILI) while preserving diaphragmatic function.
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Guidelines & protocols
TYPE 2 DIABETES IN ADULTS: MANAGEMENT
NICE
·
Endocrinology
· 2026
· 124 pages
This NICE guideline provides recommendations for the management of type 2 diabetes in adults, focusing on evidence-based practices and patient-centered care.
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Clinical notes
FIFTEEN-MINUTE CONSULTATION: A GUIDE TO PAEDIATRIC MAJOR HAEMORRHAGE
Blizard Institute, Queen Mary University of London Faculty of Medicine and Dentistry, London, UK
·
Pediatrics
· 2025
· 6 pages
This document provides a comprehensive guide on managing major haemorrhage in paediatric patients, emphasizing the importance of rapid blood product availability and the application of protocols adapted from adult data.
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Clinical reviews
CHILDHOOD GROWTH HORMONE TREATMENT: CHALLENGES, OPPORTUNITIES, AND CONSIDERATIONS
Karolinska Institutet, Stockholm, Sweden
·
Pediatric Endocrinology
· 2024
· 11 pages
This review discusses the complexities and considerations surrounding childhood growth hormone treatment, including its long-term effects and safety. It aims to provide insights into treatment goals and the approved indications for growth hormone therapy in pediatric patients.
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Clinical reviews
AWAKE VENOVENOUS EXTRACORPOREAL MEMBRANE OXYGENATION IN THE INTENSIVE CARE UNIT: CHALLENGES AND EMERGING CONCEPTS
Department of Cardiothoracic Anesthesia and ICU, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele
·
Intensive Care Medicine
· 2025
· 11 pages
This review article discusses the use of awake venovenous extracorporeal membrane oxygenation (ECMO) in patients with respiratory failure, highlighting its indications, contraindications, advantages, and disadvantages.
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Clinical reviews
PLEURAL FLUID ANALYSIS
Amit Chopra, MD; Kurt Hu, MD; David Feller-Kopman, MD; Marc A. Judson, MD
·
Pulmonology
· 2025
· 11 pages
This review provides a practical framework to maximize the diagnostic potential of pleural fluid analysis (PFA) in establishing the cause of pleural effusions. It discusses the challenges and limitations of PFA.
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Clinical reviews
PERIOPERATIVE CHEMOTHERAPY WITH FLUOROURACIL PLUS LEUCOVORIN, OXALIPLATIN, AND DOCETAXEL VERSUS FLUOROURACIL OR CAPECITABINE PLUS CISPLATIN AND EPIRUBICIN FOR LOCALLY ADVANCED, RESECTABLE GASTRIC OR GASTRO-OESOPHAGEAL JUNCTION ADENOCARCINOMA (FLOT4): A
German Cancer Consortium
·
Oncology
· 2023
· 10 pages
This study reports on the safety and efficacy of the docetaxel-based triplet FLOT as a perioperative therapy for patients with locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma.
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Clinical reviews
RESTLESS LEGS SYNDROME: A REVIEW
John W. Winkelman, MD, PhD; Benjamin Wipper, MD
·
Neurology
· 12 pages
This review discusses restless legs syndrome (RLS), a sleep-related movement disorder characterized by an overwhelming urge to move the limbs, particularly the legs, often accompanied by unpleasant sensations. It highlights the prevalence, associated conditions, and treatment options for RLS.
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Clinical reviews
EFFICACY AND SAFETY OF MINOCYCLINE IN PATIENTS WITH ACUTE ISCHAEMIC STROKE (EMPHASIS): A MULTICENTRE, DOUBLE-BLIND, RANDOMISED CONTROLLED TRIAL
Yao Lu, Ling Guan, Jialing Wu, Qianqian Yang, Meiyang Zhang, Dongyang Zhou, Hongqin Yang, Yuesong Pan, Luyan Wang, Baoshan Qiu, Chenhui Liu, Yicong Wang, Yingying Yang, Xuejiao Zhou, Hui Qu, Xiaoling Liao, Liping Liu, Xingquan Zhao, Philip M Bath, S
·
Neurology
· 2026
· 10 pages
The EMPHASIS trial investigates the efficacy and safety of minocycline in patients with acute ischaemic stroke, providing robust evidence through a multicentre, double-blind, randomised controlled trial.
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Medicines & prescribing
HEPARIN (UNFRACTIONATED): DRUG INFORMATION
Institute
·
Pharmacology
· 2026
· 69 pages
This document provides comprehensive drug information on unfractionated heparin, including dosing guidelines, contraindications, and safety considerations.
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Clinical reviews
EFFECT OF STRESS ULCER PROPHYLAXIS WITH PROTON PUMP INHIBITORS VS HISTAMINE-2 RECEPTOR BLOCKERS ON IN-HOSPITAL MORTALITY AMONG ICU PATIENTS RECEIVING INVASIVE MECHANICAL VENTILATION
The PEPTIC Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group, Alberta Health Services Critical Care Strategic Clinical Network, and the Irish Critical Care Trials Group
·
Critical Care Medicine
· 2019
· 11 pages
This study compares the in-hospital mortality rates between proton pump inhibitors (PPIs) and histamine-2 receptor blockers (H2RBs) used for stress ulcer prophylaxis in critically ill patients requiring invasive mechanical ventilation.
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Guidelines & protocols
EUROPEAN SOCIETY OF HYPERTENSION PRACTICE GUIDELINES FOR AMBULATORY BLOOD PRESSURE MONITORING
European Society of Hypertension
·
Cardiology
· 8 pages
This document provides updated recommendations for the use of ambulatory blood pressure monitoring (ABPM) in clinical practice, addressing methodological issues and clinical indications.
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Clinical reviews
PATIENT PERCEPTION OF PHYSICIAN ATTIRE: A SYSTEMATIC REVIEW UPDATE
Hwasung Medi-Science University, Fashion Institute, Dalian Art College, Medical R&D Center, Bodyfriend
·
General Medicine
· 2025
· 11 pages
This systematic review aims to update and analyze patient perceptions of physician attire, focusing on its impact on the physician–patient relationship across different medical settings and specialties.
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Clinical reviews
AGE-RELATED CHANGES IN NEUROLOGIC EXAMINATION AND SENSORY NERVE AMPLITUDE IN THE GENERAL POPULATION
Neurology®
·
Neurology
· 2023
· 8 pages
This document discusses the aging of the peripheral nervous system and its impact on neurologic examination and nerve conduction studies in the general population.
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Clinical reviews
NOT ALL HOSPITALIZED HEART FAILURE PATIENTS ARE THE SAME
Garrick C. Stewart, MD, MPH
·
Cardiology
· 5 pages
This document discusses the heterogeneity of hospitalized heart failure patients and the implications for treatment and outcomes. It highlights the increasing prevalence of heart failure and the challenges associated with hospitalizations.
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Clinical reviews
CLINICAL MANIFESTATIONS AND DIAGNOSTIC EVALUATION OF BENIGN PROSTATIC HYPERPLASIA
UpToDate, Inc.
·
Urology
· 2024
· 18 pages
This document reviews the clinical manifestations and diagnostic evaluation of benign prostatic hyperplasia (BPH), a common condition in aging males that can lead to lower urinary tract symptoms.
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Clinical reviews
ANTIBIOTIC THERAPY FOR UNCOMPLICATED ACUTE APPENDICITIS
JAMA
·
General Surgery
· 2024
· 9 pages
This document presents a ten-year follow-up study of the APPAC randomized clinical trial, assessing the effectiveness and safety of antibiotic therapy for uncomplicated acute appendicitis in adults.
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Clinical reviews
EXPLORING PANDORA’S BOX: A REVIEW OF THORACIC COMPARTMENT SYNDROME
Fundación Clínica Shaio, Universidad de La Sabana
·
Critical Care Medicine
· 2025
· 7 pages
This review systematically explores thoracic compartment syndrome (TCS), a condition that arises from increased pressure within the thoracic cavity, compromising organ function due to reduced blood flow. It aims to establish a comprehensive definition to guide diagnosis and research.
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Clinical reviews
WHAT IS A CARDIAC CT CALCIUM SCORE?
JAMA
·
Cardiology
· 2025
· 1 pages
This document explains the significance of a cardiac CT calcium score in assessing the presence of calcium in the coronary arteries, which can indicate the risk of heart disease.
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Clinical reviews
UTILITY OF INTRACARDIAC ECHOCARDIOGRAPHY FOR INFECTIVE ENDOCARDITIS AND CARDIOVASCULAR DEVICE-RELATED ENDOCARDITIS: A CONTEMPORARY SYSTEMATIC REVIEW
Cleveland Clinic
·
Cardiology
· 17 pages
This systematic review evaluates the role of intracardiac echocardiography (ICE) in diagnosing infective endocarditis (IE) and cardiovascular device-related endocarditis (CDIE), particularly in cases where traditional echocardiography methods are inconclusive.
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Clinical reviews
IRON DEFICIENCY
Health & Science University
·
Hematology
· 2026
· 16 pages
Iron deficiency is a common yet underrecognized clinical entity, particularly affecting children, menstruating and pregnant persons, and individuals of low socioeconomic status. Timely diagnosis and management are crucial to prevent iron deficiency anemia (IDA).
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