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Clinical reviews
LIGHT-BASED, ADJUNCTIVE, AND OTHER THERAPIES FOR ACNE VULGARIS
Jeffrey S Dover, MD, FRCPC, Priya Batra, MD
·
Dermatology
· 16 pages
This document reviews various light-based and adjunctive therapies for the treatment of acne vulgaris, including procedural therapies and over-the-counter products.
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Clinical reviews
OVARIAN CYSTS IN POLYCYSTIC OVARY SYNDROME
Piltonen, Kuusiniemi
·
Women's Health
· 2 pages
This research letter discusses the common misperception that polycystic ovary syndrome (PCOS) is associated with pathological ovarian cysts, highlighting the need for better understanding of ovarian morphology in women with PCOS.
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Clinical reviews
Early Anticoagulation in Acute Ischemic Stroke With Atrial Fibrillation
Inje University Ilsan Paik Hospital, National Cerebrovascular Center
·
Neurology
· 8 pages
This document discusses the importance of timely initiation of anticoagulation therapy in patients with atrial fibrillation who experience acute ischemic stroke, balancing the risks of recurrent ischemic events against potential hemorrhagic complications.
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Clinical reviews
WHY AI CANNOT DO GOOD SCIENCE WITHOUT HUMANS
General Medicine
· 1 pages
This document discusses the interplay between artificial intelligence and human researchers in scientific discovery, emphasizing the importance of human oversight and input in the research process.
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Clinical reviews
MODERATE TO SEVERE ACNE VULGARIS IN ADOLESCENTS AND ADULTS: SELECTION OF SYSTEMIC THERAPY
UpToDate, Inc.
·
Dermatology
· 2026
· 2 pages
This document discusses the selection of systemic therapy for moderate to severe acne vulgaris in adolescents and adults, highlighting the features indicative of severe cases and treatment options.
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Clinical reviews
AI IN MEDICINE
Daniel G. Aaron, MD, JD; Christopher Robertson, JD, PhD
·
General Medicine
· 2026
· 2 pages
This Viewpoint explores the groundbreaking entry of AI into clinical care, specifically focusing on a partnership in Utah that allows an AI system to prescribe medications without physician involvement.
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Clinical reviews
CORONARY ARTERY CALCIUM IN ACC/AHA PREVENTION GUIDELINES
Kyvan Irannejad, MD, Ruben Mora, MD, Srikanth Krishnan, MD, Suvasini Lakshmanan, MD, Sion Roy, MD, Matthew J. Budoff, MD
·
Cardiology
· 2026
· 5 pages
This editorial viewpoint discusses the evolution of coronary artery calcium (CAC) scoring in cardiovascular risk stratification as reflected in the ACC/AHA prevention guidelines from 2007 to 2026.
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Clinical reviews
EXTENDED LOW-DOSE APIXABAN AND SUPERFICIAL VEIN THROMBOSIS
Vanderbilt University Medical Center
·
Cardiology
· 2026
· 3 pages
This study investigates the efficacy of extended low-dose apixaban in reducing the risk of symptomatic superficial vein thrombosis (SuVT) compared to placebo.
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Clinical reviews
VITAMIN E IN THE PRIMARY PREVENTION OF CARDIOVASCULAR DISEASE AND CANCER
null
·
Cardiology
· 2005
· 10 pages
This document presents findings from the Women’s Health Study, a randomized controlled trial investigating the effects of vitamin E supplementation on cardiovascular disease and cancer risks among healthy women.
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Clinical reviews
CORONAVIRUS DISEASE (COVID-19)
Jason M. Pogue, Erin K. McCreary, Julie A. Justo
·
Infectious Diseases
· 2024
· 10 pages
This chapter provides an overview of COVID-19, including its clinical presentation, treatment guidelines, and preventive measures.
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Clinical reviews
APPENDIX 3: DRUG-INDUCED HEMATOLOGIC DISORDERS
Elisa M.
·
Pharmacology
· 6 pages
This appendix provides a comprehensive list of drugs associated with various hematologic disorders, including aplastic anemia and agranulocytosis, along with evidence ratings for their causality.
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Clinical reviews
TUCIDINOSTAT PLUS R-CHOP VS R-CHOP IN MYC/BCL2 DOUBLE-EXPRESSOR DIFFUSE LARGE B-CELL LYMPHOMA
Hematology
· 2 pages
This study aimed to assess whether adding the histone deacetylase inhibitor tucidinostat to rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) improves clinical outcomes in patients with newly diagnosed MYC/BCL2 double-expressor lymphoma.
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Clinical reviews
SURGICAL MANAGEMENT OF NONTOXIC MULTINODULAR GOITER: IS THE JURY STILL OUT?
All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
·
General Surgery
· 2015
· 2 pages
This document discusses the surgical management strategies for nontoxic multinodular goiter, comparing the efficacy of harmonic scalpel versus conventional hemostasis in thyroidectomies.
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Clinical reviews
ADVERSE EVENTS ASSOCIATED WITH FLUMAZENIL TREATMENT FOR THE MANAGEMENT OF SUSPECTED BENZODIAZEPINE INTOXICATION – A SYSTEMATIC REVIEW WITH META-ANALYSES OF RANDOMISED TRIALS
Danish Health and Medicines Authority, Bispebjerg University Hospital, Copenhagen University Hospital, Roskilde University Hospital
·
Clinical Pharmacology
· 2016
· 8 pages
This mini-review assesses the risk of serious adverse events associated with flumazenil treatment in patients with impaired consciousness due to suspected benzodiazepine overdose. It includes a systematic review and meta-analysis of randomized clinical trials comparing flumazenil treatment to placebo.
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Clinical reviews
SOCIETY FOR MATERNAL-FETAL MEDICINE STATEMENT: ACETAMINOPHEN USE DURING PREGNANCY
Society for Maternal-Fetal Medicine
·
Obstetrics
· 6 pages
This document discusses the safety and implications of acetaminophen use during pregnancy, highlighting the potential association with neurodevelopmental outcomes in children.
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Clinical reviews
EXOCRINE PANCREATIC INSUFFICIENCY
Mitchell L. Ramsey, MD; Christopher E. Forsmark, MD
·
Gastroenterology
· 2 pages
Exocrine pancreatic insufficiency is defined by a loss of pancreatic enzyme production or delivery sufficient to cause clinically significant maldigestion. The most common causes include cystic fibrosis and chronic pancreatitis.
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Clinical reviews
CAN ANTICOAGULATION BE RESUMED AFTER INTRACEREBRAL HEMORRHAGE?
UpToDate, Inc.
·
Neurology
· 2026
· 2 pages
This document discusses the considerations for resuming anticoagulation therapy following an intracerebral hemorrhage (ICH), focusing on the timing and indications based on the patient's thromboembolic risk.
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Clinical reviews
EARLY VERSUS LATER ANTICOAGULATION FOR STROKE WITH ATRIAL FIBRILLATION
University Hospital Basel, Switzerland
·
Neurology
· 2023
· 11 pages
This article investigates the effects of early versus later initiation of direct oral anticoagulants (DOACs) in patients with atrial fibrillation who have experienced an acute ischemic stroke.
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Clinical reviews
THERAPEUTIC PLASMA EXCHANGE: CORE CURRICULUM 2023
Am J Kidney Dis
·
Nephrology
· 2023
· 18 pages
This document provides a comprehensive overview of therapeutic plasma exchange (TPE), discussing its applications, technologies, and management from a nephrologist's perspective.
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Clinical reviews
NOVEL ANTIBIOTICS FOR THE TREATMENT OF INFECTIONS CAUSED BY MDR BACTERIA
Departments of Internal Medicine and Critical Care Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan
·
Infectious Disease
· 2023
· 15 pages
This document reviews the use of novel antibiotics for treating infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) bacteria. It discusses the challenges posed by these resistant strains and evaluates off-label uses versus formal recommendations.
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Clinical reviews
ACUTE MYELOID LEUKAEMIA
Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX, USA; Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of
·
Hematology
· 2023
· 14 pages
This document discusses the advancements in the treatment of acute myeloid leukaemia (AML), highlighting improved prognostication tools and treatment options over the past decade.
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Clinical reviews
RECENT ADVANCES IN ICU: Acute kidney injury
Medical University Innsbruck, University Hospital Münster, Royal Surrey Hospital Foundation Trust, University of Surrey
·
Critical Care Medicine
· 2023
· 4 pages
This document discusses recent advances in the understanding and management of acute kidney injury (AKI) in critically ill patients, emphasizing prevention and treatment strategies.
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Clinical reviews
CURRENT PRACTICE AND EVOLVING CONCEPTS IN SEPTIC SHOCK RESUSCITATION
null
·
Intensive Care
· 2021
· 16 pages
This narrative review discusses the advancements in the clinical and pathophysiological understanding of septic shock, focusing on current standards and evolving concepts in resuscitation.
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Clinical reviews
Perioperative Management of Anticoagulant and Antiplatelet Therapy
James D. Douketis, M.D., Alex C. Spyropoulos, M.D.
·
Cardiology
· 2023
· 14 pages
This review provides an evidence-based but practical approach to managing patients on anticoagulant or antiplatelet therapy who require surgery or invasive procedures.
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