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Clinical reviews
ADVANCES IN THE MANAGEMENT OF CARDIOGENIC SHOCK
Dr. Rolf M
·
Cardiology
· 12 pages
This document reviews contemporary approaches to managing patients with cardiogenic shock (CS), integrating professional society recommendations and clinical study outcomes.
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Clinical reviews
SPONTANEOUS CORONARY-ARTERY DISSECTION
Vanderbilt University Medical Center
·
Cardiology
· 2020
· 13 pages
This review article discusses spontaneous coronary-artery dissection (SCAD) as a significant cause of myocardial infarction, particularly in young women, and highlights the differences in management compared to atherosclerotic myocardial infarction.
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Clinical reviews
CRITICAL CARE HEPATOLOGY: DEFINITIONS, INCIDENCE, PROGNOSIS AND ROLE OF LIVER FAILURE IN CRITICALLY ILL PATIENTS
Aritz Perez Ruiz de Garibay, Andreas Kortgen, Julia Leonhardt, Alexander Zipprich, Michael Bauer
·
Critical Care Medicine
· 16 pages
This review discusses the definitions, incidence, and prognosis of liver failure in critically ill patients, highlighting its role in multiple organ dysfunction syndrome.
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Clinical reviews
ADVANCES IN THE MANAGEMENT OF CARDIOGENIC SHOCK
Jacob C. Jentzer, MD
·
Cardiology
· 12 pages
This document reviews contemporary approaches to the management of cardiogenic shock (CS), focusing on clinical studies and professional society recommendations.
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Clinical reviews
VASOPRESSORS IN TRAUMA: A NEVER EVENT?
Justin E. Richards, MD, Tobias Gauss, MD, Tim Harris, MD
·
Trauma Surgery
· 12 pages
This document discusses the use of vasopressors in severely injured trauma patients, highlighting the potential negative impacts on organ perfusion and mortality. It critiques the practice of hypotensive resuscitation and emphasizes the need for a balanced approach to fluid resuscitation.
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Clinical reviews
COAGULATION SUPPORT DURING PERIOPERATIVE BLEEDING MANAGEMENT
Derek J. B. Kleinveld, Nicola Curry, Jerrold H. Levy
·
Anesthesiology
· 2023
· 4 pages
This document discusses the management of perioperative bleeding, highlighting the importance of coagulation support and the use of massive transfusion protocols (MTPs) in clinical practice.
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Clinical reviews
COMPARATIVE EFFECTS OF GLUCOSE-LOWERING MEDICATIONS ON KIDNEY OUTCOMES IN TYPE 2 DIABETES
GRADE Research Group
·
Endocrinology
· 2023
· 10 pages
This study evaluates the kidney outcomes of different glucose-lowering medications in individuals with type 2 diabetes as part of the GRADE trial.
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Clinical reviews
CONTINUOUS KIDNEY REPLACEMENT THERAPIES: CORE CURRICULUM 2025
University of New Mexico, University of Ottawa, University of Alberta
·
Nephrology
· 2024
· 20 pages
This Core Curriculum provides a comprehensive review of Continuous Kidney Replacement Therapy (CKRT) for critically ill patients, detailing its application, dosing, and the multidisciplinary care required for optimal outcomes.
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Clinical reviews
HEART FAILURE THERAPY: THE FIFTH CARD
Cardiovascular Department, Pope John XXIII Hospital; Cardiology Unit, Milan Bicocca University
·
Cardiology
· 2021
· 4 pages
This document discusses the 2021 European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure, emphasizing a new approach to optimal drug therapy for patients with an ejection fraction <35%.
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Clinical reviews
SEPSIS
Mervyn Singer, Derek C Angus, Djillali Annane, Michael Bauer, Andre C Kalil, Michael Klompas, Flavia R Machado, Greg S Martin, Adrienne G Randolph, Manu Shankar-Hari, Nathan I Shapiro, Greet Van den Berghe
·
Critical Care Medicine
· 13 pages
This document provides a comprehensive overview of sepsis, defined as a dysregulated host response to infection leading to life-threatening organ dysfunction. It discusses the epidemiology, pathophysiology, patient management, and future developments related to sepsis.
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Clinical reviews
PERIOPERATIVE VASOPRESSOR MANAGEMENT IN NONCARDIAC SURGICAL PATIENTS
Dr. Legrand
·
Anesthesiology
· 13 pages
This document discusses the management of arterial pressure during noncardiac surgeries, focusing on the use of vasopressors to maintain adequate blood pressure and organ perfusion.
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Clinical reviews
WHEN HEADACHE MEETS VISUAL DISTURBANCE: AN EVIDENCE-BASED REVIEW OF COMMON AND CRITICAL ENTITIES
Shusheng Jiao, Xiaocui Han
·
Neurology
· 2026
· 15 pages
This narrative review addresses the diagnostic challenges posed by concurrent headache and visual symptoms, ranging from benign to life-threatening conditions. It synthesizes data from various studies into a structured diagnostic framework.
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Clinical reviews
RECENT TOPICS AND ADVANCED THERAPIES IN CHRONIC GRANULOMATOUS DISEASE
Japan Human Cell Society
·
Immunology
· 2022
· 13 pages
This review covers the current topics in chronic granulomatous disease (CGD) and the relationship between reactive oxygen species (ROS) and ROS-mediated pathophysiological phenomena.
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Clinical reviews
BIOMARKERS TO IMPROVE PREOPERATIVE PREDICTION OF MAJOR CARDIAC OUTCOMES AFTER NON-CARDIAC SURGERY
UMC Utrecht, Utrecht, The Netherlands; University Health Network, Toronto, Ontario, Canada; Julius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht, The Netherlands; Cochrane Netherlands, UMC Utrecht, Utrecht, The Netherlands
·
Anesthesiology
· 2022
· 3 pages
This document reviews the use of biomarkers in enhancing the predictive accuracy of the Revised Cardiac Risk Index (RCRI) for major adverse cardiac events (MACE) in patients undergoing non-cardiac surgery.
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Clinical reviews
TEN MYTHS ABOUT ALBUMIN
Springer-Verlag GmbH
·
Critical Care Medicine
· 2022
· 4 pages
This document addresses ten common misconceptions about albumin, particularly in the context of critical care, and summarizes the current evidence surrounding its use.
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Clinical reviews
CEREBRAL HEMORRHAGE: PATHOPHYSIOLOGY, TREATMENT, AND FUTURE DIRECTIONS
Circulation Research
·
Neurology
· 26 pages
This review article focuses on the epidemiology, cause, mechanisms of injury, current treatment strategies, and future research directions of intracerebral hemorrhage (ICH).
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Clinical reviews
SGLT2 Inhibitors: A New Therapeutical Strategy to Improve Clinical Outcomes in Patients with Chronic Kidney Diseases
Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro; Division of Cardiology, Università degli Studi di Napoli 'Federico II'
·
Nephrology
· 14 pages
This manuscript reviews the effects of sodium-glucose cotransport protein 2 inhibitors (SGLT2is) in patients with chronic kidney disease, focusing on their benefits for cardiac and renal complications.
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Clinical reviews
ASSOCIATED FACTORS OF PNEUMONIA IN INDIVIDUALS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) APART FROM THE USE OF INHALED CORTICOSTEROIDS
Unidad Salud Mental, Hospital Vázquez Díaz; UGC de Alergología, Hospital Universitario Virgen Macarena; Hospital Quirón Sagrado Corazón; Department of Stomatology, Faculty of Dentistry, University of Seville
·
Pulmonology
· 16 pages
This review discusses the association between inhaled corticosteroids (ICSs) and the risk of pneumonia in individuals with chronic obstructive pulmonary disease (COPD), while also exploring other potential causes of pneumonia in this patient population.
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Clinical reviews
CLINICAL PHARMACOLOGY OF ANTIHYPERTENSIVE THERAPY FOR THE TREATMENT OF HYPERTENSION IN CKD
Indiana University School of Medicine; Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana
·
Nephrology
· 2019
· 8 pages
This document reviews the mechanisms and indications for major classes of antihypertensive drugs in the context of chronic kidney disease (CKD), emphasizing the importance of hypertension management in this population.
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Clinical reviews
HYponatraemia IN HEART FAILURE: TIME FOR NEW SOLUTIONS?
Medical University of Warsaw, Almazov National Medical Research Centre, National Medical Research Center for Therapy and Preventive Medicine, University of Glasgow
·
Cardiology
· 7 pages
This document reviews the prevalence and implications of hyponatraemia in heart failure, highlighting its association with increased mortality and morbidity. It discusses established and emerging therapies aimed at improving sodium homeostasis in heart failure patients.
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Clinical reviews
PREECLAMPSIA UP TO DATE — WHAT’S GOING ON?
Japanese Society of Hypertension
·
Obstetrics and Gynecology
· 2023
· 8 pages
This mini-review discusses the latest knowledge on prediction, prevention, management, and long-term outcomes of preeclampsia, a hypertensive disorder in pregnancy, and its association with COVID-19.
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Clinical reviews
THE AMINO ACID ARGININE: A COMPREHENSIVE REVIEW
Department of Clinical Pharmacy, Faculty of Pharmacy, Mutah University; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Mutah University; Department of Allied Medical Science, University College, Al-Balqa Applied University
·
Nutrition
· 11 pages
This review covers the classification, production, and molecular mechanisms of arginine, as well as its role as a biomarker in various diseases and its therapeutic potential in treating several disorders.
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Clinical reviews
STROKE AND NEUROCOGNITIVE IMPAIRMENT COMPENDIUM
Jessica Magid-Bernstein, Romuald Girard, Sean Polster, Abhinav Srinath, Sharbel Romanos, Issam A. Awad, Lauren H. Sansing
·
Neurology
· 26 pages
This review article focuses on the epidemiology, cause, mechanisms of injury, current treatment strategies, and future research directions of intracerebral hemorrhage (ICH).
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Clinical reviews
PROTOCOL KIDNEY BIOPSY IN THE MANAGEMENT OF PROLIFERATIVE (CLASS III/IV) LUPUS NEPHRITIS: BARKING UP THE WRONG TREE!
Mayo Clinic College of Medicine and Science, Rochester, MN, USA
·
Nephrology
· 19 pages
This document reviews the role of repeat kidney biopsies in managing lupus nephritis, arguing that the practice is based on faulty evidence and offers limited benefit. It emphasizes the importance of monitoring immunological activity rather than relying solely on histological findings.
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