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Clinical reviews
INDIVIDUALISED ANTIMICROBIAL DOSE OPTIMISATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMISED CONTROLLED TRIALS
Maria Sanz Codina, Haktan Övul Bozkir, Anselm Jorda, Markus Zeitlinger
PDF202336 pages1.8 MB
The review evaluates the effectiveness of individualized antimicrobial dosing compared to standard dosing protocols. It discusses various patient populations, outcomes, and the implications of dose optimization on clinical results, including mortality and treatment failure rates. The analysis highlights the need for larger sample sizes and objective endpoints in future studies to better assess the impact of individualized dosing on patient outcomes.
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