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Clinical reviews
PRINCIPLES OF FLUID MANAGEMENT
Manu L. N. G. Malbrain, Niels Van Regenmortel, Bernd Saugel, Brecht De Tavernier, Pieter‑Jan Van Gaal, Olivier Joannes‑Boyau, Jean‑Louis Teboul, Todd W. Rice, Monty Mythen, Xavier Monnet
PDF201816 pages1.9 MB
The article addresses the complexities of fluid therapy in septic shock, emphasizing the importance of timing, type, and dosage of intravenous fluids. It introduces the 'four D’s' of fluid therapy: drug, dosing, duration, and de-escalation. The review outlines four phases of fluid therapy—resuscitation, optimization, stabilization, and evacuation—while posing critical questions regarding fluid administration. The findings are grounded in recent studies and clinical guidelines.
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