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Clinical reviews
LOWER VS HIGHER FLUID VOLUMES IN ADULT PATIENTS WITH SEPSIS - AN UPDATED SYSTEMATIC REVIEW WITH META-ANALYSIS AND TRIAL SEQUENTIAL ANALYSIS
Praleene Sivapalan, M.D., Karen L. Ellekjaer, M.D., Marie K. Jessen, Ph.D, Tine S. Meyhoff, M.D., Maria Cronhjort, Ph.D., Peter B. Hjortrup, Ph.D., Jørn Wetterslev, Ph.D., Anders Granholm, M.D., Morten H. Møller, Ph.D., Anders Perner, Ph.D.
PDF2023141 pages17.4 MB
The article provides a comprehensive analysis of existing studies regarding fluid volume management in sepsis, highlighting the importance of optimal fluid resuscitation in improving patient outcomes. It includes trial sequential analysis to assess the robustness of the findings. The systematic review synthesizes data from multiple trials, offering insights into the efficacy of different fluid management strategies in critically ill patients.
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