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Clinical reviews
DURATION OF ANTIBIOTIC THERAPY: WITH OR WITHOUT BIOMARKERS?
Department of Critical Care Medicine, Hospital de São Francisco Xavier, Unidade Local de Saúde de Lisboa Ocidental, Lisbon, Portugal; NOVA Medical School, Comprehensive Health Research Centre, NOVA University of Lisbon, Lisbon, Portugal; Center for
PDF11 pages1.6 MB
Antibiotic use and overuse has risen dramatically during recent decades, leading to a concerning increase in multidrug-resistant pathogens. Antimicrobial resistance has emerged as a critical global health challenge, with significant mortality associated with bacterial AMR. The document reviews various studies and trials that explore the effectiveness of biomarker-guided strategies in optimizing antibiotic therapy duration, particularly in intensive care settings. It highlights the variability in current practices and the urgent need for high-quality evidence to guide optimal prescribing policies.
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