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Duke University School of Medicine, Yale School of Medicine, McMaster University, Chinese University of Hong Kong
The American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) aims to provide a comprehensive review of potassium-competitive acid blockers (P-CABs) as a therapeutic option. It discusses their role in the healing and maintenance of erosive esophagitis and evaluates the evidence regarding their efficacy compared to standard therapies. The document also addresses the cost implications and the lack of randomized comparisons with double-dose PPIs, highlighting the need for cautious integration into clinical practice.
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