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Clinical reviews
Hepatitis E Virus, Second Edition (Springer, 2023)
Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College
PDF261 pages8.7 MB
This second‑edition volume in the Advances in Experimental Medicine and Biology series presents up‑to‑date research on Hepatitis E virus (HEV). It details advances in cell culture techniques, the construction of infectious cDNA clones, and the role of adaptive mutations in viral replication. The book also reviews pre‑clinical models, including organoid and chimeric mouse systems, and evaluates antiviral agents such as Sofosbuvir, ribavirin, niclosamide, and novel rocaglates. Emerging insights into host‑virus interactions and immune responses in immunocompromised patients are discussed, providing a valuable resource for clinicians and researchers in hepatology and infectious diseases.
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