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Clinical reviews
MATERNAL DEATH: LESSONS FOR ANAESTHESIA AND CRITICAL CARE
Queen Charlotte’s and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK; New York-Presbyterian Weill Cornell Medical Center, New York, USA
·
Anaesthesiology
· 2022
· 8 pages
This article discusses the implications of maternal death for anaesthesia and critical care, highlighting key considerations and processes for reporting and review in the UK and USA.
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Clinical reviews
OVERVIEW OF HYPOTHERMIA, ITS ROLE IN NEUROPROTECTION, AND THE APPLICATION OF PROPHYLACTIC HYPOTHERMIA IN TRAUMATIC BRAIN INJURY
Christine Trieu, MD; Suman Rajagopalan, MD, FASA; W. Andrew Kofke, MD, MBA, FNCS; Jovany Cruz Navarro, MD
·
Neurosurgery
· 2023
· 10 pages
This review examines the pathophysiology of traumatic brain injury (TBI) and discusses the benefits and risks of induced hypothermia in TBI patients. It also summarizes the latest trials and addresses inconsistencies in the literature regarding hypothermia's effects.
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Clinical reviews
WHEN IS IT SAFE TO RESUME ANTICOAGULATION IN TRAUMATIC BRAIN INJURY?
null
·
Neurosurgery
· 2022
· 6 pages
This document reviews the timing and safety of resuming anticoagulation therapy following traumatic brain injury (TBI), highlighting the controversies and recent findings in the field.
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Clinical reviews
ACUTE PULMONARY EMBOLISM: A REVIEW
null
·
Pulmonary Medicine
· 2022
· 10 pages
This review discusses the characteristics, diagnosis, and management of pulmonary embolism (PE), emphasizing the importance of clinical assessment and imaging in patients presenting with symptoms.
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Clinical reviews
CLINICAL OUTCOMES OF INTENSIVE INPATIENT BLOOD PRESSURE MANAGEMENT IN HOSPITALIZED OLDER ADULTS
Timothy S. Anderson, MD, MAS; Shoshana J. Herzig, MD, MPH; Bocheng Jing, MS; W. John Boscardin, PhD; Kathy Fung, MS; Edward R. Marcantonio, MD, SM; Michael A. Steinman, MD
·
Internal Medicine
· 2023
· 9 pages
This study examines the association of intensive treatment of elevated inpatient blood pressures with in-hospital clinical outcomes in older adults hospitalized for noncardiac conditions.
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Clinical reviews
CHRONIC KIDNEY DISEASE DIAGNOSIS AND MANAGEMENT
null
·
Nephrology
· 11 pages
This document provides a comprehensive review of chronic kidney disease (CKD), emphasizing the importance of screening, diagnosis, and management by primary care clinicians to prevent adverse outcomes.
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Clinical reviews
ATRIAL FIBRILLATION AND HEART FAILURE: NOVEL INSIGHTS INTO THE CHICKEN AND EGG DILEMMA
Department of Internal Medicine II, University Medical Centre Regensburg; Clinic for Cardiology and Pneumology, Georg-August University Göttingen
·
Cardiology
· 3 pages
This document explores the complex relationship between atrial fibrillation (AF) and heart failure, highlighting how these two conditions can exacerbate each other and affect patient prognosis.
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Clinical reviews
DIRECT ORAL ANTICOAGULANTS VS LOW-MOLECULAR-WEIGHT HEPARIN AND RECURRENT VTE IN PATIENTS WITH CANCER
JAMA
·
Hematology
· 2023
· 10 pages
This study evaluates the effectiveness of direct oral anticoagulants (DOACs) compared to low-molecular-weight heparin (LMWH) in preventing recurrent venous thromboembolism (VTE) in patients with cancer.
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Clinical reviews
DIAGNOSIS AND MANAGEMENT OF AUTOIMMUNE HEPATITIS
DIMEC, Università di Bologna and IRCCS Policlinico di Sant'Orsola, Bologna, Italy; Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany
·
Hepatology
· 2023
· 18 pages
This document provides a comprehensive overview of autoimmune hepatitis, including its clinical presentation, diagnostic criteria, and treatment options. It emphasizes the importance of early diagnosis and appropriate management to prevent progression to liver cirrhosis.
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Clinical reviews
RISK PREDICTION IN PATIENTS WITH DIABETES: IS SCORE 2D THE PERFECT SOLUTION?
Karolinska University Hospital, Munich Helmholtz Center
·
Endocrinology
· 2023
· 3 pages
This editorial discusses the SCORE 2D risk prediction model for estimating 10-year cardiovascular risk in patients with type 2 diabetes in Europe, evaluating its applicability and limitations.
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Clinical reviews
NEONATAL HYPERBILIRUBINEMIA: EVALUATION AND TREATMENT
Duke University School of Medicine; Uniformed Services University of the Health Sciences; Naval Hospital Camp Pendleton Family Medicine Residency Program
·
Pediatrics
· 10 pages
This document provides an overview of neonatal hyperbilirubinemia, focusing on its evaluation and treatment protocols. It emphasizes the importance of screening for risk factors and the appropriate use of phototherapy.
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Clinical reviews
INTRAVENOUS FLUID THERAPY IN ACCORDANCE WITH KIDNEY INJURY RISK: WHEN TO PRESCRIBE WHAT VOLUME OF WHICH SOLUTION
Koc University School of Medicine, Istanbul, Turkey; Universidad Autonoma de Madrid; Vall d’Hebron University Hospital, Universitat Autònoma de Barcelona
·
Nephrology
· 2023
· 9 pages
This narrative review updates the approach to intravenous fluid therapy in hospitalized patients, focusing on the timing, type, amount, and infusion rate of fluids, particularly in the context of acute kidney injury (AKI).
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Clinical reviews
EFFECTS OF RELOCATION OF SEDENTARY TIME AND PHYSICAL ACTIVITY IN OLDER ADULTS WITH DIABETES MELLITUS
Universidade Federal do Triângulo Mineiro, Universidade do Estado da Bahia
·
Endocrinology
· 2023
· 7 pages
This study estimates the hypothetical effects of substituting time spent in moderate-to-vigorous physical activity (MVPA) and time spent in sedentary behavior (SB) on diabetes among older adults.
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Clinical reviews
PROPOSED NEW CLASSIFICATION FOR ACUTE CORONARY SYNDROME
UConn Health, Texas Tech University Health Sciences Center, Cedars-Sinai Smidt Heart Institute
·
Cardiology
· 2023
· 5 pages
This document presents a new classification for acute coronary syndrome (ACS) that emphasizes the need for immediate reperfusion in certain cases. It discusses the limitations of current classifications and proposes an updated framework based on recent evidence.
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Clinical reviews
EMERGING THERAPIES IN B-THALASSEMIA
American University
·
Hematology
· 14 pages
This document provides an overview of novel therapeutic agents currently in development for beta-thalassemia, focusing on their potential to improve patient outcomes.
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Clinical reviews
RESISTANT HYPERTENSION IN DIALYSIS
Medical University of Warsaw, Warsaw, Poland
·
Nephrology
· 2023
· 8 pages
This document discusses the prevalence and management of resistant hypertension in patients undergoing dialysis, highlighting its significance as a cardiovascular risk factor.
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Clinical reviews
PREVALENCE OF VENOUS INFARCTION IN PATIENTS WITH CEREBRAL VENOUS THROMBOSIS: BASELINE DIFFUSION-WEIGHTED MRI AND FOLLOW-UP MRI
Eiman Alajmi, MD; Jeremy Zung, MD; Marie Duquet-Armand, MD; Jonathan M. Coutinho, MD, PhD; Daniel M. Mandell, MD, PhD
·
Neurology
· 7 pages
This study investigates the prevalence of venous infarction in patients with cerebral venous thrombosis (CVT) using diffusion-weighted MRI. It aims to clarify the relationship between neuroimaging findings and clinical outcomes in CVT management.
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Clinical reviews
RATIONALE AND STRATEGIES FOR PRESERVING RESIDUAL KIDNEY FUNCTION IN DIALYSIS PATIENTS
State University of New York Downstate Medical Center; Georgetown University
·
Nephrology
· 2019
· 11 pages
This document reviews the importance of residual kidney function (RKF) in dialysis patients and discusses various strategies to preserve it. It highlights the survival benefits associated with RKF and the mechanisms that may contribute to its preservation.
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Clinical reviews
ANTIBIOTIC MYTHS FOR THE INFECTIOUS DISEASES CLINICIAN
University of Pittsburgh School of Medicine; Duke University Medical Center; Temple University
·
Infectious Diseases
· 2023
· 13 pages
This document addresses common misconceptions regarding the use of antimicrobials, particularly focusing on the nuanced considerations for various antibiotics as understood by infectious diseases specialists.
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Clinical reviews
MEASURING ENHANCED RECOVERY IN OBSTETRICS: A NARRATIVE REVIEW
Janny Xue Chen Ke, MD, MSc; Sarah Ciechanowicz, BMBCh, MRes; Nadir Sharawi, MBBS, MSc; Pervez Sultan, MBChB, MD (Res), FRCA
·
Obstetrics
· 10 pages
This article reviews the protocolized approach to enhanced recovery after cesarean delivery, highlighting its impact on maternal and neonatal outcomes. It summarizes findings from various studies on the effectiveness of this approach.
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Clinical reviews
MANAGEMENT OF BLEEDING IN PATIENTS ON DIRECT ORAL ANTICOAGULANTS IN EMERGENCY DEPARTMENT: WHERE WE ARE AND WHERE WE ARE GOING
Department of Emergency Medicine, San Giovanni Addolorata Hospital, Rome, Italy
·
Emergency Medicine
· 2023
· 5 pages
This document discusses the management of bleeding in patients taking direct oral anticoagulants (DOACs) in the emergency department, highlighting the critical nature of such cases and the need for appropriate therapeutic strategies.
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Clinical reviews
CSF PRESSURE, VOLUME, AND POST-DURAL PUNCTURE HEADACHE: A CASE-CONTROL STUDY AND SYSTEMATIC REVIEW
American Headache Society
·
Neurology
· 2019
· 15 pages
This document presents a systematic literature review and a case-control study evaluating the associations between post-dural puncture headache (PDPH) and cerebrospinal fluid (CSF) pressure and volume. The study aims to identify novel risk factors for PDPH.
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Clinical reviews
THE ROLE OF RNA INTERFERENCE IN FUNCTIONAL CURE STRATEGIES FOR CHRONIC HEPATITIS B
Jeremy S Nayagam, Zillah C Cargill, Kosh Agarwal
·
Hepatology
· 2020
· 8 pages
This review highlights the challenges and advancements in RNA interference (RNAi) therapeutics for chronic hepatitis B (CHB), focusing on its potential as a functional cure strategy.
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Clinical reviews
HYBRID IMMUNITY MORE PROTECTIVE THAN PRIOR SARS-CoV-2 INFECTION ALONE
Infectious Disease
· 2023
· 2 pages
This document discusses the findings of a systematic review indicating that individuals with hybrid immunity have better protection against the Omicron variant of SARS-CoV-2 compared to those with only prior infection.
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