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Clinical reviews
REAL-WORLD STUDY OF INTRANASAL KETAMINE FOR USE IN PATIENTS WITH REFRACTORY CHRONIC MIGRAINE: A RETROSPECTIVE ANALYSIS
Thomas Jefferson University, OhioHealth, Rush University
·
Neurology
· 7 pages
This study evaluates the effectiveness and tolerability of intranasal ketamine in patients with refractory chronic migraine through a retrospective analysis.
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Clinical reviews
NONTYPHOIDAL SALMONELLA INVASIVE DISEASE: CHALLENGES AND SOLUTIONS
Centre for International Health, University of Otago; Malawi Liverpool Wellcome Trust Programme; Institute of Infection, Veterinary, and Ecological Sciences, University of Liverpool; Department of Pathology, Kamuzu University of Health Sciences;
·
Infectious Diseases
· 2023
· 6 pages
This article discusses the significant public health challenge posed by nontyphoidal Salmonella invasive disease in sub-Saharan Africa, highlighting the epidemiology, clinical implications, and potential solutions including vaccine development.
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Clinical reviews
PREOPERATIVE HYPERTENSION: PERIOPERATIVE IMPLICATIONS AND MANAGEMENT
Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Medical Research at St James’s, St James’s University Hospital, Leeds, UK
·
Anaesthesiology
· 2021
· 7 pages
This article discusses the management of patients with hypertension in the perioperative setting, emphasizing the importance of individualized preoperative decisions based on overall cardiac risk rather than solely on blood pressure readings.
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Clinical reviews
EFFECTIVENESS OF LATERAL DECUBITUS POSITION FOR PREVENTING POST-DURAL PUNCTURE HEADACHE: A META-ANALYSIS
Universidad del Valle, The Johns Hopkins University, University of Manitoba
·
Anesthesiology
· 2017
· 9 pages
This meta-analysis investigates the effectiveness of the lateral decubitus position in preventing post-dural puncture headache (PDPH) during lumbar punctures. It compares the incidence of PDPH between patients positioned laterally versus those in a sitting position.
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Clinical reviews
EMERGENCY MEDICINE UPDATES: SPONTANEOUS BACTERIAL PERITONITIS
SAUSHEC, Emergency Medicine, Brooke Army Medical Center; Department of Emergency Medicine, Rush University Medical Center
·
Emergency Medicine
· 2023
· 6 pages
This paper evaluates key evidence-based updates concerning spontaneous bacterial peritonitis (SBP) for emergency clinicians, highlighting its commonality in patients with cirrhosis and ascites.
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Clinical reviews
CARE OF THE PATIENT WITH ABNORMAL KIDNEY TEST RESULTS
Division of Nephrology, Department of Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco
·
Nephrology
· 2023
· 17 pages
This article reviews the evaluation and management of patients with abnormal kidney test results, focusing on kidney function and damage. It provides recommendations for clinicians on follow-up actions and lifestyle modifications.
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Clinical reviews
THE ASSOCIATION BETWEEN DIETARY PATTERNS, PLASMA LIPID PROFILES, AND INFLAMMATORY POTENTIAL IN A VASCULAR DEMENTIA COHORT
Department of Aged Care and Rehabilitation, Bankstown-Lidcombe Hospital; Faculty of Medicine, University of New South Wales; School of Life and Environmental Sciences, University of Sydney
·
Neurology
· 2023
· 8 pages
This original article investigates the associations between dietary patterns, plasma lipid profiles, and inflammatory potential in individuals with vascular dementia compared to healthy controls.
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Clinical reviews
OUTCOMES OF DIGOXIN VS. BETA BLOCKER IN ATRIAL FIBRILLATION: REPORT FROM ESC–EHRA EORP AF LONG-TERM GENERAL REGISTRY
University of Belgrade, Universitaire Trousseau, University of Modena and Reggio Emilia, University of Murcia, University of Liverpool, Clinical Center of Serbia, Aalborg University, Uppsala University
·
Cardiology
· 2022
· 11 pages
This study evaluates the safety and effects of digoxin compared to beta-blocker therapy in patients with atrial fibrillation (AF). It aims to clarify the associated risks of digoxin therapy, particularly concerning mortality and quality of life.
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Clinical reviews
MATERNAL CRITICAL CARE: PART I
NHS Trust, Nottingham, UK; Guy’s and St Thomas’ Hospital NHS Foundation Trust, London, UK; Nottingham University Hospitals
·
Obstetrics
· 2021
· 8 pages
This article focuses on the provision of critical care for peripartum women, covering general principles and common conditions encountered in critical care settings.
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Clinical reviews
ROLE OF INCRETIN-BASED THERAPY IN HOSPITALIZED PATIENTS WITH TYPE 2 DIABETES
Department of Internal Medicine, Specialities Hospital, National Medical Center 'La Raza', Instituto Mexicano del Seguro Social, Mexico City, Mexico
·
Endocrinology
· 2 pages
This document discusses the management of hyperglycemia in hospitalized patients with type 2 diabetes, focusing on the role of incretin-based therapies. It highlights the complexities and risks associated with traditional insulin therapies and presents evidence supporting the use of dipeptidyl peptidase-4 inhibitors.
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Clinical reviews
HYPERCALCEMIA: A REVIEW
Marcella Donovan Walker, MD; Elizabeth Shane, MD
·
Endocrinology
· 2022
· 13 pages
This review discusses the prevalence, causes, and management of hypercalcemia, emphasizing its clinical significance and treatment options.
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Clinical reviews
Management of Azoospermia: A Systematic Approach
Department of Reproductive Medicine, Birmingham Women's and Children's NHS Foundation Trust; Department of Urology, University College London Hospital; Centre for Human Reproductive Science, School of Medical Sciences, University of Birmingham
·
Reproductive Medicine
· 2026
· 13 pages
This document provides a systematic approach to the management of azoospermia, detailing the work-up process, causes, and treatment options available for affected men.
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Clinical reviews
RIGHT VENTRICULAR DIASTOLIC DYSFUNCTION AND FAILURE: A REVIEW
Youn-Hoa Jung, Xianfeng Ren, Giancarlo Suffredini, Jeffery M. Dodd-o, Wei Dong Gao
·
Cardiology
· 2021
· 14 pages
This review discusses right ventricular diastolic dysfunction and failure (RVDDF), highlighting its association with various cardiovascular diseases and its implications for clinical management.
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Clinical reviews
COMPARATIVE EFFECTIVENESS OF AZITHROMYCIN VERSUS ROFLUMILAST IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: EMULATED TARGET TRIAL
Brigham and Women's Hospital, Harvard Medical School, Lady Davis Institute for Medical Research, McGill University, University of California, Los Angeles
·
Pulmonology
· 2026
· 12 pages
This study compares the risk of moderate or severe exacerbations of chronic obstructive pulmonary disease (COPD) among new users of azithromycin versus roflumilast in routine clinical practice.
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Clinical reviews
THE HUMAN BURDEN OF MESOAMERICAN NEPHROPATHY: DIAGNOSIS AND TREATMENT IN A COMPLEX WEB OF SOCIOECONOMICS, CONTEXT, AND STIGMA
Ramón Antonio García-Trabanino, MD, MSc, FASN, FSLANH
·
Nephrology
· 7 pages
This document discusses Mesoamerican endemic nephropathy, a chronic kidney disease prevalent in specific regions, highlighting its diagnosis, treatment challenges, and the socio-economic factors affecting patient care.
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Clinical reviews
Management of Azoospermia: A Systematic Approach
Department of Reproductive Medicine, Birmingham Women's and Children's NHS Foundation Trust; Department of Urology, University College London Hospital; Centre for Human Reproductive Science, School of Medical Sciences, University of Birmingham
·
Reproductive Medicine
· 2026
· 13 pages
This document provides a systematic approach to the management of azoospermia, detailing the work-up process, causes, and management strategies, including surgical options.
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Clinical reviews
ERECTILE DYSFUNCTION AND CARDIOVASCULAR HEALTH
Emil Durukan, Christian Fuglesang S. Jensen, Kristoffer Grundtvig Skaarup, Mikkel Fode
·
Urology
· 2023
· 8 pages
This document discusses the relationship between erectile dysfunction (ED) and cardiovascular health, highlighting how ED can serve as an early indicator of cardiovascular disease.
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Clinical reviews
ATRIAL FIBRILLATION: OVERVIEW OF MANAGEMENT
Kapil Kumar, MD
·
Cardiology
· 2026
· 48 pages
This document provides a comprehensive overview of the management of atrial fibrillation (AF), the most commonly treated cardiac arrhythmia, focusing on both initial and long-term management strategies.
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Clinical reviews
GUIDELINE WATCH ROUNDUP
Brigham and Women's Hospital
·
Cardiology
· 2026
· 27 pages
Summaries and highlights of the most important new clinical guidelines to inform your practice.
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Clinical reviews
AGA CLINICAL PRACTICE UPDATE ON MANAGEMENT OF PORTAL VEIN THROMBOSIS IN PATIENTS WITH CIRRHOSIS: EXPERT REVIEW
American Gastroenterological Association
·
Gastroenterology
· 2025
· 10 pages
This Clinical Practice Update provides best practice advice for the evaluation and management of portal vein thrombosis (PVT) in patients with cirrhosis, focusing on the role of direct oral anticoagulants and endovascular interventions.
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Clinical reviews
HIP FRACTURES
Fjola Johannesdottir, PhD; Jimmie E. Roberts, PhD; Douglas P. Kiel, MD, MPH; Joy N. Tsai, MD
·
Orthopedics
· 12 pages
This document provides a comprehensive review of hip fractures, including their classification, risk factors, and management strategies. It highlights the significant impact of hip fractures on mortality and functional recovery.
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Clinical reviews
SEVERE HYPERNATREMIA IN THE EMERGENCY DEPARTMENT: A RETROSPECTIVE, SINGLE-CENTER STUDY
Japanese Society of Nephrology
·
Emergency Medicine
· 2026
· 6 pages
This study investigates the clinical characteristics and early management patterns of patients with severe hypernatremia presenting to the emergency department. It highlights the high mortality associated with this condition and the need for careful management.
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Clinical reviews
EPIDEMIOLOGY, RISK FACTORS, AND PREVENTION OF ATRIAL FIBRILLATION
UpToDate, Inc.
·
Cardiology
· 2026
· 34 pages
This document provides an overview of the epidemiology, risk factors, and prevention strategies related to atrial fibrillation.
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Clinical reviews
CARDIAC IMPLANTABLE ELECTRONIC DEVICE-INDUCED TRICUSPID REGURGITATION: IMPLICATIONS AND MANAGEMENT
Massachusetts General Hospital, Boston, Massachusetts, USA
·
Cardiology
· 2024
· 9 pages
This document discusses tricuspid regurgitation (TR) secondary to cardiac implantable electronic devices (CIEDs), highlighting its implications and management strategies.
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