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Clinical reviews
PATIENT-LEVEL META-ANALYSIS OF LOW-DOSE HYDROCORTISONE IN ADULTS WITH SEPTIC SHOCK
Romain Pirracchio, M.D., M.P.H., Ph.D., Djillali Annane, M.D., Ph.D.
·
Critical Care Medicine
· 12 pages
This article presents a patient-level meta-analysis investigating the effects of low-dose hydrocortisone on adults with septic shock, focusing on mortality and adverse events.
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Clinical reviews
INITIAL STATIN DOSE AFTER MYOCARDIAL INFARCTION AND LONG-TERM CARDIOVASCULAR OUTCOMES
Turku University Hospital and University of Turku
·
Cardiology
· 2022
· 9 pages
This study investigates the impact of initial statin dosing on long-term cardiovascular outcomes in patients after myocardial infarction (MI). It highlights the suboptimal real-life dosing of statins and its implications for patient outcomes.
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Clinical reviews
PERIOPERATIVE CONSIDERATIONS IN MANAGEMENT OF THE SEVERELY BLEEDING COAGULOPATHIC PATIENT
Gabor Erdoes, M.D., Ph.D., David Faraoni, M.D., Ph.D., Andreas Koster, M.D., Marie E. Steiner, M.D., Kamrouz Ghadimi, M.D., M.H.Sc., F.A.H.A., Jerrold H. Levy, M.D., F.C.C.M.
·
Anesthesiology
· 2023
· 26 pages
This document discusses the multifactorial pathophysiology of bleeding in severely coagulopathic patients and outlines management strategies for perioperative bleeding, including the evaluation of bleeding risk and administration of transfusional therapies.
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Clinical reviews
DIAGNOSIS AND MANAGEMENT OF CIRRHOSIS AND ITS COMPLICATIONS
null
·
Gastroenterology
· 2023
· 14 pages
This document provides a comprehensive review of cirrhosis, its causes, symptoms, and management strategies, highlighting the increasing mortality rates associated with the condition.
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Clinical reviews
A Review of Bicarbonate Use in Common Clinical Scenarios
University of California at San Diego
·
Emergency Medicine
· 2023
· 26 pages
This article reviews the use of bicarbonate therapy in various clinical situations, particularly focusing on its efficacy and recommendations in conditions like diabetic ketoacidosis and cardiac arrest.
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Clinical reviews
CURRENT AND EMERGING PHARMACOTHERAPY FOR THE MANAGEMENT OF HYPERTROPHIC CARDIOMYOPATHY
New York Medical College, Rowan-Virtua School of Osteopathic Medicine, MedStar Union Memorial Hospital, Tufts University School of Medicine, Westchester Medical Center, Atlantic Health
·
Cardiology
· 2023
· 13 pages
This document provides a comprehensive review of current and emerging pharmacotherapy options for managing hypertrophic cardiomyopathy (HCM), a common genetic heart disease.
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Clinical reviews
THE INTENSITY OF ORGAN SUPPORT: RESTRICTIVE OR AGGRESSIVE THERAPY FOR CRITICALLY ILL PATIENTS
Department of Intensive Care Medicine, The First Hospital of Jilin University
·
Intensive Care Medicine
· 5 pages
This article discusses the intensity of organ support in critically ill patients, evaluating the mechanisms, benefits, and potential complications of aggressive versus restrictive therapeutic strategies.
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Clinical reviews
MANAGEMENT OF OLIGURIA
Springer-Verlag GmbH Germany, part of Springer Nature
·
Nephrology
· 2022
· 4 pages
This document discusses the management of oliguria in critically ill patients, distinguishing between physiological and pathological causes. It emphasizes the importance of identifying the underlying reasons for oliguria to guide appropriate treatment.
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Clinical reviews
CURRENT PRACTICE IN THE PERIOPERATIVE MANAGEMENT OF PATIENTS WITH DIABETES MELLITUS: A NARRATIVE REVIEW
Department of Anaesthesiology & Perioperative Medicine, Mater University Hospital, School of Medicine, University College Dublin, Dublin, Ireland; Academic Medical Centre, Amsterdam, the Netherlands; Outcomes Research Cleveland Clinic, Cleveland, OH, USA
·
Anaesthesiology
· 2023
· 11 pages
This narrative review summarizes the current guidelines and evidence regarding the perioperative management of patients with diabetes mellitus, focusing on preoperative assessment, insulin management, glycaemic control, and postoperative care.
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Clinical reviews
PREVENTION OF UPPER GASTROINTESTINAL BLEEDING IN CRITICAL ILLNESS
Springer-Verlag GmbH Germany, part of Springer Nature
·
Intensive Care Medicine
· 2023
· 3 pages
This document discusses the risk of stress ulcers and gastrointestinal bleeding in critically ill patients, emphasizing the role of pharmacologic prophylaxis in prevention.
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Clinical reviews
TRAUMA IN PREGNANCY
R Adams Cowley Shock Trauma Center, University of Maryland Medical Center
·
Obstetrics and Gynecology
· 23 pages
This document discusses the significant burden of traumatic injuries during pregnancy, highlighting the physiological changes that necessitate modifications in resuscitation and management strategies.
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Clinical reviews
EFFICACY AND SAFETY OF PIPERACILLIN-TAZOBACTAM COMPARED WITH MEROPENEM IN TREATING COMPLICATED URINARY TRACT INFECTIONS INCLUDING ACUTE PYELONEPHRITIS DUE TO EXTENDED-SPECTRUM β-LACTAMASE-PRODUCING ENTEROBACTERIACEAE
Zhejiang University, China; Charles Sturt University, Australia; Kharkiv Medical Academy of Postgraduate Education, Ukraine
·
Infectious Disease
· 2023
· 11 pages
This study compares the efficacy and safety of piperacillin-tazobactam (PTZ) and meropenem in treating complicated urinary tract infections, particularly those caused by extended-spectrum β-lactamase-producing Enterobacteriaceae.
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Clinical reviews
MANAGEMENT OF HYPERTENSIVE EMERGENCIES AND URGENCIES: NARRATIVE REVIEW
Medical Units of Dumfries and Galloway Royal Infirmary, Queen Elizabeth University Hospital
·
Cardiology
· 2021
· 7 pages
This article reviews current guidelines and recommendations for the management of hypertensive emergencies and urgencies, focusing on user-friendly strategies for general physicians.
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Clinical reviews
WHEN IS ENTERAL NUTRITION INDICATED?
University of Missouri – Columbia, The Johns Hopkins Hospital, Cleveland Clinic, Morrison Healthcare at Atrium Health Navicant, Christiana Care Health System, Froedtert Hospital, David Geffen School of Medicine at UCLA, Sodexo/Billings Clinic, Parkview
·
Nutrition
· 2022
· 27 pages
This document discusses the indications for enteral nutrition, focusing on various clinical scenarios and evidence-based recommendations.
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Clinical reviews
RENAL FUNCTION IN THE ICU: ALWAYS LOOK BOTH WAYS BEFORE INITIATING VENOUS THROMBOPROPHYLAXIS
Centro Hospitalar e Universitário de Coimbra EPE, Serviço de Medicina Intensiva, Coimbra, Portugal
·
Intensive Care Medicine
· 2023
· 2 pages
This correspondence discusses the importance of monitoring renal function and adjusting pharmacological thromboprophylaxis in critically ill patients, particularly those with augmented renal clearance (ARC).
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Clinical reviews
BALANCED MULTIELECTROLYTE SOLUTION VERSUS SALINE IN CRITICALLY ILL ADULTS
The George Institute for Global Health, Australia
·
Intensive Care Medicine
· 2022
· 12 pages
This study investigates whether the use of balanced multielectrolyte solution (BMES) instead of saline reduces the risk of acute kidney injury or death in critically ill patients.
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Clinical reviews
INVASIVE CANDIDIASIS: CURRENT CLINICAL CHALLENGES AND UNMET NEEDS IN ADULT POPULATIONS
Department of Infectious Diseases, Hospital Clinic of Barcelona, IDIBAPS, CIBERINF, University of Barcelona, Barcelona, Spain; CHU UCL Godinne Namur, UCL Louvain Medical School, Namur, Belgium; Symmetron Ltd, London, UK; Radboudumc-CWZ Center of
·
Infectious Diseases
· 17 pages
This review summarizes the main issues underlying the management of adults affected by invasive candidiasis (IC), focusing on specific forms of the infection and the challenges faced in clinical practice.
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Clinical reviews
Hypertension in Patients Treated With In-Center Maintenance Hemodialysis: Current Evidence and Future Opportunities: A Scientific Statement From the American Heart Association
American Heart Association
·
Nephrology
· 2023
· 11 pages
This scientific statement reviews the current evidence on defining, diagnosing, and treating hypertension in patients treated with maintenance hemodialysis, highlighting opportunities for future investigation.
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Clinical reviews
SODIUM POLYSTYRENE IS UNSAFE AND SHOULD NOT BE PRESCRIBED FOR THE TREATMENT OF HYPERKALEMIA: PRIMUM NON NOCERE!
Université de Lorraine, Centre d’Investigations Cliniques- Plurithématique, CHRU Nancy; Princess Grace Hospital, Monaco; University of Michigan School of Medicine
·
Nephrology
· 2023
· 9 pages
This document discusses the safety concerns associated with the use of sodium polystyrene sulfonate for treating hyperkalemia, highlighting its poor tolerability and lack of evidence for chronic use.
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Clinical reviews
ANCILLARY TESTING FOR NEUROLOGIC DETERMINATION OF DEATH IN ADULTS: IN SEARCH OF A SURROGATE OF CLINICAL FUNCTION
Springer-Verlag GmbH Germany, part of Springer Nature
·
Intensive Care Medicine
· 2023
· 3 pages
This document discusses the determination of death by neurologic criteria (DNC) and the role of ancillary tests in assessing cerebral blood flow, perfusion, and activity. It highlights the complexities and advancements in neurocritical care that influence DNC.
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Clinical reviews
EFFECTS OF ASPIRIN ON KIDNEY BIOPSY BLEEDING COMPLICATIONS – A SYSTEMATIC REVIEW AND META-ANALYSIS
Miguel Relvas, Joana Gonçalves, Inês Castro, Hugo Diniz, Luís Mendonça, Luís Coentrão
·
Nephrology
· 28 pages
This systematic review and meta-analysis examines the association between aspirin use and bleeding complications during percutaneous kidney biopsy (PKB). The study analyzes data from multiple primary studies to determine the risk of major bleeding events in patients exposed to aspirin compared to those who were not.
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Clinical reviews
NaCl 3% BOLUS THERAPY AS EMERGENCY TREATMENT FOR SEVERE HYPONATREMIA: COMPARISON OF 100 ML VERSUS 250 ML
Rijnstate Hospital Arnhem
·
Internal Medicine
· 22 pages
This study compares the efficacy and safety of 100 ml versus 250 ml NaCl 3% bolus therapy as initial treatment for severe hypotonic hyponatremia. It aims to determine the optimal volume for rapid serum sodium elevation.
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Clinical reviews
LIPID MEASUREMENTS IN THE MANAGEMENT OF CARDIOVASCULAR DISEASES: PRACTICAL RECOMMENDATIONS
Emory University School of Medicine; Atlanta Veterans Affairs Medical Center; Johns Hopkins University School of Medicine; St. David’s Medical Center; University of Chicago School of Medicine; Centers for Disease Control and Prevention; Rigshospitalet,
·
Cardiology
· 20 pages
This document provides practical recommendations for lipid measurements crucial in managing patients at risk for atherosclerotic cardiovascular diseases, including coronary heart disease and stroke.
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Clinical reviews
QUANTIFICATION OF LIVER IRON OVERLOAD WITH MRI: REVIEW AND GUIDELINES FROM THE ESGAR AND SAR
University of Wisconsin; University of Texas Southwestern Medical Center; Centro Hospitalar Universitário do Porto; Instituto de Investigación Sanitaria La Fe; Donostia University Hospital; University Hospital and University of Rennes 1; Medical
·
Radiology
· 10 pages
This document provides a comprehensive review and guidelines on the quantification of liver iron overload using MRI techniques. It discusses various methodologies, their reproducibility, and clinical implications.
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