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Clinical reviews
NaCl 3% BOLUS THERAPY AS EMERGENCY TREATMENT FOR SEVERE HYPONATREMIA: COMPARISON OF 100 ML VERSUS 250 ML
Rijnstate Hospital Arnhem
PDF22 pages698 KB
The initial treatment of severe hyponatremia focuses on rapidly increasing serum sodium to mitigate complications such as cerebral edema. This retrospective analysis evaluates the effectiveness of two different bolus volumes of NaCl 3% in achieving this goal. The study includes data from 130 adults with severe hypotonic hyponatremia, assessing outcomes such as serum sodium rise and the risk of overcorrection. The findings suggest that a 250 ml bolus is more effective than a 100 ml bolus in achieving the desired serum sodium increase.
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