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Clinical reviews
IMPACT OF DAPAGLIFLOZIN ON CARDIAC REMODELING IN PATIENTS WITH CHRONIC HEART FAILURE: DAPA-MODA STUDY
Hospital Clínico Universitario Virgen de la Arrixaca, Universidad de Murcia, Centro Nacional de Investigaciones Cardiovasculares Carlos III
·
Cardiology
· 2023
· 24 pages
This document discusses the effects of dapagliflozin on cardiac remodeling in patients with chronic heart failure, highlighting findings from the DAPA-MODA study.
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Clinical reviews
COMPENDIUM ON INCREASED RISK OF CARDIOVASCULAR COMPLICATIONS IN CHRONIC KIDNEY DISEASE
Michel Burnier, Aikaterini Damianaki
·
Nephrology
· 2023
· 14 pages
This document discusses the relationship between hypertension and chronic kidney disease (CKD), highlighting hypertension as a significant risk factor for cardiovascular complications in CKD patients.
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Clinical reviews
MANAGEMENT OF MITRAL STENOSIS: A SYSTEMATIC REVIEW OF CLINICAL PRACTICE GUIDELINES AND RECOMMENDATIONS
King's College Hospital, Morriston Cardiac Regional Centre, Newham University Hospital, Barts Health NHS Trust, G.d'Annunzio University, Lund University, Casa di Cura Villa Serena, NIHR Barts Biomedical Research Centre
·
Cardiology
· 2021
· 17 pages
This document systematically reviews existing guidelines for the diagnosis and management of mitral stenosis (MS), highlighting their similarities and differences to guide clinical decision-making.
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Clinical reviews
DIRECT ORAL ANTICOAGULANTS VERSUS WARFARIN ACROSS THE SPECTRUM OF KIDNEY FUNCTION: PATIENT-LEVEL NETWORK META-ANALYSES FROM COMBINE AF
Josephine Harrington, MD; Anthony P. Carnicelli, MD; Kaiyuan Hua, MS; Lars Wallentin, MD, PhD; Manesh R. Patel, MD; Stefan H. Hohnloser, MD; Robert P. Giugliano, MD, ScM; Keith A.A. Fox, MB, ChB; Ziad Hijazi, MD, MPH; Renato D. Lopes, MD, MHS, PhD; Sean
·
Cardiology
· 10 pages
This study evaluates the safety and efficacy of direct oral anticoagulants (DOACs) compared to warfarin in patients with varying levels of kidney function using data from the COMBINE AF database.
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Clinical reviews
IDENTIFYING PATIENTS AT HIGH RISK OF LEFT ATRIAL APPENDAGE THROMBUS BEFORE CARDIOVERSION: THE CLOTS-AF SCORE
Journal of the American Heart Association
·
Cardiology
· 2023
· 17 pages
This study evaluates clinical and echocardiographic parameters to predict the risk of left atrial appendage thrombus (LAAT) in patients undergoing transesophageal echocardiography before cardioversion.
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Clinical reviews
A RAPID REVIEW OF THE RED EYE
University of Pittsburgh
·
Ophthalmology
· 6 pages
This review article discusses the common presenting complaint of red eye, emphasizing the importance of accurate diagnosis and management of various conditions, including ocular emergencies.
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Clinical reviews
DIAGNOSIS AND TREATMENT OF HYPONATREMIA: COMPILATION OF THE GUIDELINES
Erasmus Medical Center, Rotterdam, The Netherlands
·
Nephrology
· 2017
· 10 pages
This document reviews the diagnosis and treatment of hyponatremia, comparing guidelines from the United States and Europe while highlighting recent developments in the field.
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Clinical reviews
PRACTICAL “1-2-3-4-DAY” RULE FOR STARTING DIRECT ORAL ANTICOAGULANTS AFTER ISCHEMIC STROKE WITH ATRIAL FIBRILLATION: COMBINED HOSPITAL-BASED COHORT STUDY
Shunsuke Kimura, MD; Kazunori Toyoda, MD; Sohei Yoshimura, MD; Kazuo Minematsu, MD; Masahiro Yasaka, MD; Maurizio Paciaroni, MD; David J. Werring, MD; Hiroshi Yamagami, MD; Takehiko Nagao, MD; Shinichi Yoshimura, MD; Alexandros Polymeris, MD; Annaelle
·
Neurology
· 10 pages
This study investigates the optimal timing for initiating direct oral anticoagulants (DOACs) in patients with nonvalvular atrial fibrillation following acute ischemic stroke or transient ischemic attack, focusing on practical guidelines based on stroke severity.
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Clinical reviews
CONSENSUS STATEMENT ON THE CURRENT PHARMACOLOGICAL PREVENTION AND MANAGEMENT OF HEART FAILURE
Andrew P Sindone, Carmine De Pasquale, John Amerena, Christine Burdeniuk, Alicia Chan, Andrew Coats, David L Hare, Peter Macdonald, Aaron Sverdlov, John J Atherton
·
Cardiology
· 2022
· 6 pages
This document presents a consensus statement focusing on the evaluation of new and established drugs for the prevention and treatment of heart failure, reflecting updates since the 2018 guidelines.
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Clinical reviews
THE REFEEDING SYNDROME: A NEGLECTED BUT POTENTIALLY SERIOUS CONDITION FOR INPATIENTS. A NARRATIVE REVIEW
Valentina Ponzo, Marianna Pellegrini, Iolanda Cioffi, Luca Scaglione, Simona Bo
·
Nutrition
· 2020
· 12 pages
This narrative review discusses the Refeeding Syndrome (RFS), a serious condition that can occur when individuals are rapidly fed after a period of severe undernourishment. It highlights the importance of awareness and management of RFS to prevent complications.
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Clinical reviews
INCLISIRAN: PRESENT AND FUTURE PERSPECTIVES OF A NEW EFFECTIVE LDL CHOLESTEROL-LOWERING AGENT
Graecia University
·
Cardiology
· 8 pages
This document reviews inclisiran, a small interfering RNA that has proven its safety and efficacy in reducing LDL-cholesterol, highlighting its development, mechanism of action, and current recommendations in clinical practice.
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Clinical reviews
MANAGING THE PHYSIOLOGICALLY DIFFICULT AIRWAY IN CRITICALLY ILL ADULTS
Craig Steven Jabaley
·
Critical Care
· 2023
· 7 pages
This article reviews the challenges and strategies for airway management in critically ill adults, particularly focusing on the physiologically difficult airway.
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Clinical reviews
MANAGEMENT OF VENTRICULAR ARRHYTHMIAS WORLDWIDE
American College of Cardiology Foundation
·
Cardiology
· 2023
· 14 pages
This document compares the latest guidelines for the management of ventricular arrhythmias and the prevention of sudden cardiac death from various cardiology societies.
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Clinical reviews
THE HEART FAILURE KNIGHTS
Department of Medicine, ASST Mantova, C. Poma Hospital, Italy
·
Cardiology
· 2023
· 21 pages
This article discusses the 2021 European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure, focusing on optimal drug therapy and the introduction of new treatment options.
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Clinical reviews
TEN THINGS ICU SPECIALISTS NEED TO KNOW ABOUT DIRECT ORAL ANTICOAGULANTS (DOACS)
Springer-Verlag GmbH Germany, part of Springer Nature and ESICM
·
Intensive Care Medicine
· 2018
· 4 pages
This document outlines ten crucial points that ICU specialists should be aware of regarding the use of direct oral anticoagulants (DOACs) in critically ill patients.
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Clinical reviews
FLUID THERAPY FOR CRITICALLY ILL ADULTS WITH SEPSIS
Fernando G. Zampieri, MD, PhD; Sean M. Bagshaw, MD, MSc; Matthew W. Semler, MD, MSc
·
Critical Care Medicine
· 14 pages
This review discusses the importance of fluid therapy in the management of sepsis in critically ill adults, detailing the phases of fluid therapy and its impact on patient outcomes.
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Clinical reviews
AIRWAY MANAGEMENT IN PREGNANCY
Rachel A. Achu, Sharon C. Reale
·
Obstetrics
· 2023
· 7 pages
This review highlights the current evidence on airway management in obstetric patients, focusing on strategies to minimize the use of general anesthesia when possible.
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Clinical reviews
STATINS REVISITED: THERAPEUTIC APPLICATIONS BEYOND LIPID LOWERING?
Cardiovascular Program-ICCC, IR-Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Cardiology Hospital Clinic, IDIBAPS, Spain
·
Cardiology
· 2023
· 3 pages
This editorial discusses the therapeutic applications of statins beyond their lipid-lowering effects, particularly in the context of coronary artery bypass grafting (CABG). It highlights recent studies and their implications for clinical practice.
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Clinical reviews
PERSPECTIVES ON PERIPHERAL PERFUSION ASSESSMENT
Hospital
·
Critical Care
· 7 pages
This article summarizes the pathophysiological determinants of capillary refill time (CRT), reviews new technical developments in peripheral perfusion assessment, and explores evidence on the role of CRT monitoring in septic shock and other critical conditions.
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Clinical reviews
ADJUNCTIVE VASOPRESSORS IN DISTRIBUTIVE SHOCK: HOW SOON IS EARLY?
Bruno Garcia and Matthieu Legrand
·
Critical Care Medicine
· 3 pages
This document discusses the timing and administration strategies of adjunctive vasopressors in patients with distributive shock, particularly focusing on the evidence surrounding early versus late administration.
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Clinical reviews
UPDATES FOR CARDIO- KIDNEY PROTECTIVE EFFECTS BY ANGIOTENSIN RECEPTOR- NEPRILYSIN INHIBITOR: REQUIREMENT FOR ADDITIONAL EVIDENCE OF KIDNEY PROTECTION
City University
·
Cardiology
· 14 pages
This contemporary review discusses the potential cardio-kidney protective effects of Angiotensin Receptor-Neprilysin Inhibitor (ARNI) and the need for further evidence regarding its renoprotective capabilities.
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Clinical reviews
NEW INSIGHTS INTO THE FLUID MANAGEMENT IN PATIENTS WITH SEPTIC SHOCK
National and Kapodistrian University of Athens, Greece
·
Critical Care Medicine
· 2023
· 20 pages
This review discusses the latest advancements in fluid management strategies for patients experiencing septic shock, emphasizing the importance of dynamic assessments of fluid responsiveness.
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Clinical reviews
IMPORTANT PATIENT PHENOTYPES IN PRIMARY HFPEF
Heart Failure Association (HFA) and the European Heart Rhythm Association (EHRA) of the ESC, and the European Society of Hypertension (ESH)
·
Cardiology
· 51 pages
This document discusses patient phenotype profiling in heart failure with preserved ejection fraction (HFpEF) to guide therapeutic decision-making.
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Clinical reviews
PERITONEAL DIALYSIS
Colorado School of Medicine
·
Nephrology
· 2021
· 10 pages
This review article discusses the use of peritoneal dialysis in the treatment of end-stage kidney disease (ESKD), highlighting its prevalence, benefits, and challenges in clinical practice.
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