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Resources
24 shown
Clinical reviews
ACUTE KIDNEY INJURY
John A. Kellum, Paola Romagnani, Gloria Ashuntantang, Claudio Ronco, Alexander Zarbock, Hans-Joachim Anders
·
Nephrology
· 2021
· 17 pages
This primer discusses acute kidney injury (AKI), characterized by a sudden loss of kidney function, and its implications in various healthcare settings. It highlights the importance of early detection and management strategies to prevent long-term consequences.
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Clinical reviews
DIURETIC TREATMENT IN HEART FAILURE
Oregon Clinical and Translational Research Institute, Oregon Health and Science University; Duke University School of Medicine
·
Cardiology
· 2017
· 12 pages
This review discusses the pharmacologic principles of diuretic therapy in heart failure, integrating recent research data and suggesting evidence-based approaches for treatment.
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Clinical reviews
SLEEP DISORDERS IN CHRONIC KIDNEY DISEASE
Department of Medicine, University of Toronto; Department of Medicine, Women's College Hospital; Women's College Research Institute; Sleep Research Laboratory, Toronto Rehabilitation Institute, KITE-UHN
·
Nephrology
· 2024
· 11 pages
This document discusses the prevalence and impact of sleep disorders in patients with chronic kidney disease (CKD), highlighting conditions such as restless legs syndrome, insomnia, and sleep apnoea.
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Clinical reviews
PHARMACOTHERAPY FOR ESSENTIAL HYPERTENSION: A BRIEF REVIEW
Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, US
·
Cardiology
· 2022
· 12 pages
This document reviews pharmacotherapy for hypertension, addressing treatment strategies, medication efficacy, and the challenges of achieving blood pressure goals.
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Clinical reviews
INTERVENTIONS FOR ADULT CONGENITAL HEART DISEASE
Quebec Heart & Lung Institute, Laval University; Hospital Clinic, IDIBAPS; Toronto Congenital Cardiac Centre for Adults, University Health Network; UCLA Adult Congenital Heart Disease Center
·
Cardiology
· 2025
· 17 pages
This review evaluates the available transcatheter interventions for adult patients with congenital heart disease (CHD), highlighting advances in imaging diagnostics and surgical techniques that have improved patient outcomes.
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Clinical reviews
ACUTE DYSPNEA IN THE EMERGENCY DEPARTMENT: A CLINICAL REVIEW
Pierachille Santus, Dejan Radovanovic, Marina Saad, Camilla Zilianti, Silvia Coppola, Davide Alberto Chiumello, Matteo Pecchiari
·
Emergency Medicine
· 2023
· 17 pages
This clinical review focuses on the pathophysiology of acute dyspnea, its clinical presentation, and evaluation, including ultrasound-based diagnostic workup, as well as available non-invasive modalities of respiratory support.
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Clinical reviews
PROBIOTICS IN THE ICU: A SCOPING REVIEW OF EVIDENCE FOR INFECTION PREVENTION
BMC
·
Critical Care Medicine
· 15 pages
This scoping review examines the efficacy of probiotics in preventing ICU-acquired infections (ICU-AIs) in critically ill patients, highlighting the influence of strain specificity, intervention duration, and dosage.
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Clinical reviews
NATRIURETIC PEPTIDES: ROLE IN THE DIAGNOSIS AND MANAGEMENT OF HEART FAILURE: A SCIENTIFIC STATEMENT FROM THE HEART FAILURE ASSOCIATION OF THE EUROPEAN SOCIETY OF CARDIOLOGY, HEART FAILURE SOCIETY OF AMERICA AND JAPANESE HEART FAILURE SOCIETY
Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America, Japanese Heart Failure Society
·
Cardiology
· 18 pages
This review article discusses the role of natriuretic peptides, specifically BNP and NT-proBNP, in the diagnosis and management of heart failure. It highlights their importance as biomarkers and their implications for therapeutic approaches.
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Clinical reviews
TRICUSPID VALVE DISEASE: UPDATES ON DIAGNOSTIC IMAGING AND INTERVENTION
Brigham and Women’s Hospital, Harvard Medical School, and various institutions across Europe and North America
·
Cardiology
· 2026
· 13 pages
This review article discusses the advancements in diagnostic imaging and intervention for tricuspid valve disease, particularly focusing on tricuspid regurgitation and the technological innovations in transcatheter therapies.
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Clinical reviews
UNCOMPLICATED CHOLEDOCHOLITHIASIS IN ELDERLY PATIENTS: A TARGET TRIAL EMULATION COMPARING OBSERVATION AND ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY
Medical College of Wisconsin
·
Gastroenterology
· 2026
· 11 pages
This study investigates the management of uncomplicated choledocholithiasis in elderly patients, comparing the outcomes of early endoscopic retrograde cholangiopancreatography (ERCP) versus observation.
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Clinical reviews
IMMUNO‑INFLAMMATORY MECHANISMS IN THE CHRONIFICATION OF PAIN
Universidad Mayor de San Andrés, La Paz, Bolivia; Pain Medicine and Column Center at Randall
·
Pain Medicine
· 2026
· 22 pages
This narrative review synthesizes current understanding of cellular and molecular immuno-inflammatory processes underlying the transition from acute to chronic pain, emphasizing therapeutic implications of immune-neural interactions.
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Clinical reviews
Definitions of non-response and response to biological therapy for severe asthma: a systematic review
ERJ Open Research
·
Pulmonology
· 2023
· 53 pages
This systematic review explores the definitions of non-response and response to biological therapy in patients with severe asthma. It aims to clarify these concepts to improve treatment outcomes and patient management.
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Clinical reviews
Tinnitus
Trinity College Dublin, University of Otago, University of Illinois Urbana-Champaign, University of Regensburg, Universidad de Granada, University of Sydney, Eastern Switzerland University of Applied Sciences, Chennai Institute of Technology, Instituto
·
Otolaryngology
· 2026
· 22 pages
This document provides a comprehensive overview of tinnitus, a condition characterized by the perception of sound without an external source, affecting a significant portion of the adult population. It discusses the underlying mechanisms, diagnosis, and management strategies for tinnitus.
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Clinical reviews
THE ROLE OF SGLT-2 INHIBITORS IN THE MANAGEMENT OF PATIENTS WITH TYPE 2 DIABETES
KIRUDDU NATIONAL REFERRAL HOSPITAL
·
Endocrinology
· 49 pages
This document discusses the role of SGLT-2 inhibitors in managing type 2 diabetes, highlighting their mechanisms, benefits, and clinical guidelines for use in patients with diabetes and chronic kidney disease.
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Clinical reviews
THERAPY OF TYPE 2 DIABETES: MORE GLIFLOZINES AND LESS METFORMIN?
S. Maria della Misericordia Hospital, Perugia, Italy; University of Insubria, Varese, Italy
·
Endocrinology
· 6 pages
This document discusses the evolving treatment landscape for Type 2 diabetes, focusing on the role of gliflozines compared to metformin. It highlights the cardiovascular and renal benefits of newer anti-diabetic medications.
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Clinical reviews
NUTRITION INTERVENTIONS FOR ADULTS WITH DYSLIPIDEMIA: A CLINICAL PERSPECTIVE FROM THE NATIONAL LIPID ASSOCIATION
Midwest Biomedical Research, Kasiska Division of Health Sciences, Idaho State University, University of California Irvine Heart Disease Prevention Program, Department of Nutritional Sciences, Texas Tech University, Herbert Wertheim School of Public
·
Nutrition
· 2023
· 24 pages
This Clinical Perspective provides an update on nutrition interventions for managing dyslipidemia in adults, focusing on the three most common types: low-density lipoprotein cholesterol (LDL-C) elevation, triglyceride elevation, and mixed dyslipidemia.
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Clinical reviews
LOW-FLOW ACUTE KIDNEY INJURY
Bruce A. Molitoris
·
Nephrology
· 2022
· 11 pages
This document reviews the pathophysiology of prerenal azotemia, abdominal compartment syndrome, and obstructive uropathy as causes of acute kidney injury (AKI). It emphasizes the importance of early recognition and correction of underlying processes to prevent severe outcomes.
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Clinical reviews
JOURNAL CLUB ARTICLE PRESENTATION (2)
Dr. Mulinzi Solomon
·
Infectious Disease
· 2023
· 40 pages
Review of a study investigating the efficacy of standard-dose dolutegravir-based antiretroviral therapy (ART) in individuals co-treated for tuberculosis, particularly concerning drug interactions with rifampicin.
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Clinical reviews
PRE-ECLAMPSIA AWARENESS MONTH PRESENTATION
Kawempe National Referral Hospital
·
Obstetrics & Gynecology
· 11 pages
An analysis of severe maternal morbidity and mortality, focusing on hypertensive disorders of pregnancy (PET), eclampsia, hemorrhage, and sepsis at Kawempe National Referral Hospital.
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Clinical reviews
HOW I PERSONALIZE FLUID THERAPY IN SEPTIC SHOCK?
Xavier Monnet, Christopher Lai, Jean‑Louis Teboul
·
Critical Care
· 2023
· 11 pages
This review discusses the personalization of fluid therapy in septic shock, highlighting the need to tailor fluid management based on patient characteristics and clinical situations. It addresses the challenges and considerations in fluid administration during septic shock.
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Clinical reviews
IDENTIFYING A REFRACTORY SHOCK PHENOTYPE IN PEDIATRIC SEPSIS USING A VASOACTIVE-ADJUSTED SHOCK INDEX
Northwestern University Feinberg School of Medicine, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, University of Colorado School of Medicine, University of Washington School of Medicine, Yale School of Medicine, Boston
·
Pediatrics
· 2026
· 10 pages
This document discusses the identification of a refractory shock phenotype in pediatric sepsis through the use of a vasoactive-adjusted shock index. It highlights the clinical implications and outcomes associated with this phenotype.
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Clinical reviews
NECROTIZING PANCREATITIS: A REVIEW FOR THE ACUTE CARE SURGEON
Henry Ford Hospital
·
Surgery
· 2020
· 8 pages
This article provides a comprehensive review of necrotizing pancreatitis, focusing on management recommendations for acute care surgeons. It discusses the epidemiology, diagnosis, treatment options, and complications associated with this condition.
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Clinical reviews
BLOOD PRESSURE MANAGEMENT IN NEUROLOGIC EMERGENCIES
College
·
Emergency Medicine
· 19 pages
This document provides a comprehensive framework for managing blood pressure in various neurologic emergencies, including stroke and traumatic brain injury (TBI). It emphasizes the importance of timely and effective intervention to reduce morbidity and mortality.
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Clinical reviews
SEPSIS-INDUCED DISSEMINATED INTRAVASCULAR COAGULATION: AN INTERNATIONAL ESTRANGEMENT OF DISEASE CONCEPT
Osaka Medical and Pharmaceutical University, Hokkaido University Faculty of Medicine, Kakogawa Acute Care Medical Center
·
Critical Care Medicine
· 9 pages
This mini review discusses the differences in the diagnosis and treatment of disseminated intravascular coagulation (DIC) associated with sepsis between Japan and Western countries, highlighting the need for patient selection in therapeutic strategies.
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