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Sepsis & Septic Shock

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  • Airway & Mechanical Ventilation
  • Sepsis & Septic Shock
  • Trauma & Acute Care
  • Basic Emergency Care (A&E)
  • Obstetric Emergencies

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  • Airway & Mechanical Ventilation8 resourcesAIRWAY MANAGEMENT ED TM (2) · PLANNING PATIENT PREPARATION AIRWAY ASSESSMENT PERFORMED …
  • Sepsis & Septic Shock12 resourcesSURVIVING SEPSIS CAMPAIGN: INTERNATIONAL GUIDELINES FOR MANAGEMENT OF SEPSIS AND SEPTIC SHOCK 2021 · 2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department …
  • Trauma & Acute Care12 resourcesInitial Trauma Assessment · Management of Chest Trauma …
  • Basic Emergency Care (A&E)12 resourcesQUICK REFERENCE GUIDE FOR PHYSICIANS, PROVIDERS, NURSES, AND PARAMEDICS · Ottawa Handbook of Emergency Medicine …
  • Obstetric Emergencies13 resourcesClinical Management of Obstetric and Neonatal Emergencies in Africa · MATERNAL COLLAPSE IN PREGNANCY AND THE PUERPERIUM …
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Showing collection Sepsis & Septic Shock, 12 resources

Sepsis & Septic Shock

Surviving Sepsis guidance, lactate, cultures, fluids vs vasopressors, adjunctive pressors, steroids and source control.

12 shown

This collection provides resources on the management of sepsis and septic shock, focusing on guidelines, treatment strategies, and the use of lactate levels. It is intended for clinicians and students seeking to understand the latest practices in sepsis care.

National and international guidance

  1. 01SURVIVING SEPSIS CAMPAIGN: INTERNATIONAL GUIDELINES FOR MANAGEMENT OF SEPSIS AND SEPTIC SHOCK 2021 coverGuidelines & protocolsSURVIVING SEPSIS CAMPAIGN: INTERNATIONAL GUIDELINES FOR MANAGEMENT OF SEPSIS AND SEPTIC SHOCK 2021Canada·Critical Care Medicine· 2021· 81 pagesThis document provides guidelines for the management of sepsis and septic shock in adult patients, emphasizing the importance of early identification and appropriate management.Start here — Surviving Sepsis 2021
  2. 022023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department coverClinical reviews2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency DepartmentDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara·Emergency Medicine· 2023· 23 pagesThis review aims to update physicians on the main pillars of treatment for sepsis and septic shock, including empirical antimicrobial treatment, fluid replacement, and vasoactive agents. The management of sepsis and septic shock has significantly progressed in the last few years, and improving knowledge of the main therapeutic cornerstones is crucial to achieve better patient outcomes.2023 ED update
  3. 03PROVISION AND RATIONAL USE OF BLOOD CULTURE BOTTLES TO IMPROVE SEPSIS AND BLOODSTREAM INFECTION DIAGNOSIS coverGuidelines & protocolsPROVISION AND RATIONAL USE OF BLOOD CULTURE BOTTLES TO IMPROVE SEPSIS AND BLOODSTREAM INFECTION DIAGNOSISMinistry of Health, Uganda·Infectious Disease· 2025· 2 pagesThis document outlines the guidelines for the appropriate use of blood culture bottles to enhance the diagnosis of sepsis and bloodstream infections in Uganda. It emphasizes the importance of timely and accurate diagnosis to improve patient outcomes.Blood cultures done right

Further clinical reference

  1. 04SEPTIC SHOCK: CURRENT OPINION IN CRITICAL CARE coverClinical reviewsSEPTIC SHOCK: CURRENT OPINION IN CRITICAL CAREWashington University·Critical Care· 2026· 8 pagesThis review aims to provide a summary of recent updates in resuscitation and vasopressor strategies for septic shock, as well as advancements in precision therapy.Read: p. 1Current opinion in critical care
  2. 05CURRENT PRACTICE AND EVOLVING CONCEPTS IN SEPTIC SHOCK RESUSCITATION coverClinical reviewsCURRENT PRACTICE AND EVOLVING CONCEPTS IN SEPTIC SHOCK RESUSCITATIONnull·Intensive Care· 2021· 16 pagesThis narrative review discusses the advancements in the clinical and pathophysiological understanding of septic shock, focusing on current standards and evolving concepts in resuscitation.Read: Current practice · pp. 1–2Resuscitation — evolving concepts
  3. 06VASOPRESSORS OR FLUIDS IN EARLY SEPTIC SHOCK coverClinical reviewsVASOPRESSORS OR FLUIDS IN EARLY SEPTIC SHOCKThe ARISE FLUIDS Investigators, the ANZICS Clinical Trials Group, and the ACEM Clinical Trials Network·Critical Care Medicine· 2026· 12 pagesThis study investigates the optimal approach to early resuscitation in septic shock, comparing the use of vasopressors with restricted fluid volumes against higher fluid volumes with later vasopressor therapy.Read: pp. 11–12Vasopressors or fluids first?
  4. 07HOW TO USE LACTATE LEVELS TO GUIDE SEPTIC SHOCK RESUSCITATION: AN UPDATE coverClinical reviewsHOW TO USE LACTATE LEVELS TO GUIDE SEPTIC SHOCK RESUSCITATION: AN UPDATEErasmus MC University Medical Center, Bloomsbury Institute of Intensive Care Medicine·Intensive Care Medicine· 4 pagesThis document provides an update on the use of lactate levels in guiding resuscitation efforts for patients experiencing septic shock. It emphasizes the importance of considering lactate levels alongside other physiological variables rather than in isolation.Read: pp. 3–4Lactate-guided resuscitation
  5. 08FLUID THERAPY FOR CRITICALLY ILL ADULTS WITH SEPSIS coverClinical reviewsFLUID THERAPY FOR CRITICALLY ILL ADULTS WITH SEPSISFernando G. Zampieri, MD, PhD; Sean M. Bagshaw, MD, MSc; Matthew W. Semler, MD, MSc·Critical Care Medicine· 14 pagesThis review discusses the importance of fluid therapy in the management of sepsis in critically ill adults, detailing the phases of fluid therapy and its impact on patient outcomes.Read: SHOCK · p. 9Fluid therapy in sepsis

Also in this collection

  1. 09HOW WE ESCALATE VASOPRESSOR AND CORTICOSTEROID THERAPY IN PATIENTS WITH SEPTIC SHOCK coverClinical notesHOW WE ESCALATE VASOPRESSOR AND CORTICOSTEROID THERAPY IN PATIENTS WITH SEPTIC SHOCKBoston University·Critical Care Medicine· 2023· 8 pagesThis document discusses the escalation of vasopressor and corticosteroid therapy in patients experiencing septic shock, emphasizing treatment decisions and monitoring strategies.Escalating vasopressors & steroids
  2. 10ADJUNCTIVE VASOPRESSORS IN DISTRIBUTIVE SHOCK: HOW SOON IS EARLY? coverClinical reviewsADJUNCTIVE VASOPRESSORS IN DISTRIBUTIVE SHOCK: HOW SOON IS EARLY?Bruno Garcia and Matthieu Legrand·Critical Care Medicine· 3 pagesThis document discusses the timing and administration strategies of adjunctive vasopressors in patients with distributive shock, particularly focusing on the evidence surrounding early versus late administration.Adjunctive vasopressors — how early?
  3. 11VASOPRESSOR WEANING IN SEPTIC SHOCK: THE MISSING PIECE IN THE 2026 GUIDELINES coverClinical reviewsVASOPRESSOR WEANING IN SEPTIC SHOCK: THE MISSING PIECE IN THE 2026 GUIDELINESFederal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil·Critical Care Medicine· 2026· 2 pagesThis correspondence discusses the gaps in the 2026 Surviving Sepsis Campaign guidelines regarding the de-escalation of vasopressors during septic shock stabilization. It highlights the need for further research on the optimal strategies for vasopressor withdrawal.Vasopressor weaning
  4. 12EVALUATION OF HYDROCORTISONE, VITAMIN C, AND THIAMINE FOR THE TREATMENT OF SEPTIC SHOCK: A RANDOMIZED CONTROLLED TRIAL (THE HYVITS TRIAL) coverClinical reviewsEVALUATION OF HYDROCORTISONE, VITAMIN C, AND THIAMINE FOR THE TREATMENT OF SEPTIC SHOCK: A RANDOMIZED CONTROLLED TRIAL (THE HYVITS TRIAL)Saint Luke’s Hospital of Kansas City; Hamad General Hospital, Hamad Medical Corporation; Weill Cornell Medicine-Qatar; Al Wakra Hospital, Hamad Medical Corporation; University of North Carolina Rex Hospital; Penn State Health Milton S. Hershey Medical·Critical Care Medicine· 2023· 5 pagesThis study evaluates the effect of combined hydrocortisone, vitamin C, and thiamine on patients with septic shock in a randomized controlled trial format.Hydrocortisone–vitamin C–thiamine trial

Collection updated Sep 2026· Access follows each resource's usual availability.

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