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American College of Chest Physicians
The American College of Chest Physicians conducted a thorough review of the literature regarding platelet and fresh frozen plasma transfusions in critically ill patients. The guideline focuses on indications for transfusions in patients with thrombocytopenia, both with and without active bleeding, and outlines recommendations based on a systematic review of available evidence. A multidisciplinary expert panel developed the guidelines using the Grading of Recommendations, Assessment, Development, and Evaluations approach to ensure the recommendations are grounded in high-quality evidence.
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