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Clinical reviews
PROTOCOL KIDNEY BIOPSY IN THE MANAGEMENT OF PROLIFERATIVE (CLASS III/IV) LUPUS NEPHRITIS: BARKING UP THE WRONG TREE!
Mayo Clinic College of Medicine and Science, Rochester, MN, USA
PDF202619 pages1.4 MB
Lupus nephritis is a severe manifestation of systemic lupus erythematosus, and despite advancements in treatment, outcomes have not significantly improved. The authors argue that protocol biopsies may not provide useful information for determining the duration of immunosuppressive therapy or predicting relapse risk. They review studies that illustrate the complexities of managing LN and the limitations of relying solely on histological remission to guide treatment decisions.
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