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American College of Physicians
The guideline is based on systematic reviews assessing the comparative benefits and harms of various pharmacologic treatments for episodic migraine prevention. It evaluates the effectiveness of treatments such as beta-blockers, antidepressants, and newer CGRP antagonists. The guideline aims to assist clinicians in selecting appropriate monotherapy for nonpregnant adults with episodic migraines, emphasizing the importance of addressing underdiagnosis and undertreatment in this population.
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