pharm progressive 2016-1

Erere University College of Health Sciences

The exam consists of a short‑essay section requiring a table of drug administration routes with their advantages and disadvantages, followed by multiple‑choice questions. Topics include mechanisms of drug permeation, first‑order kinetics, plasma protein binding, biotransformation, prodrugs, metabolic reactions, enzyme induction, first‑pass metabolism, and factors influencing drug response. Additional questions focus on muscarinic agonists and antagonists, cholinesterase inhibitors, and toxic effects of organophosphate exposure. The paper was administered at Erere University College of Health Sciences on 4 April 2016.