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Clinical reviews
NEW APPROACHES TO CHRONIC HEPATITIS B
University College London, Kings College Hospital London
PDF202315 pages3.2 MB
Chronic hepatitis B is caused by the hepatitis B virus (HBV), which can lead to a range of clinical outcomes from asymptomatic infection to severe liver disease, including cirrhosis and hepatocellular carcinoma. The article provides an in-depth analysis of the virus's life cycle, therapeutic targets, and emerging treatment strategies, particularly focusing on RNA interference and novel therapeutic agents. It emphasizes the need for effective management strategies, especially in low- and middle-income countries where the disease burden is highest.
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