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Clinical reviews
MULTIPLE MYELOMA: 2026 UPDATE ON DIAGNOSIS, RISK-STRATIFICATION AND MANAGEMENT
Mayo Clinic
PDF202624 pages504 KB
The update discusses the criteria for diagnosing multiple myeloma, including the necessary presence of clonal bone marrow plasma cells and defining events. It also outlines the risk stratification for high-risk multiple myeloma based on genetic markers. The document details initial therapy options, including a quadruplet regimen for eligible patients and alternative treatments for frail patients. Maintenance therapy recommendations are also provided, emphasizing the role of lenalidomide and monoclonal antibodies.
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