INTERNATIONAL CONSENSUS GUIDELINES FOR THE OPTIMAL USE OF THE POLYMYXINS

School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York; Detroit Medical Center; Department of Internal Medicine, Medical School, Universidade Federal do Rio Grande do Sul; Infectious Diseases Institute, Rambam

The guidelines provide recommendations for the use of polymyxins in treating infections caused by multidrug-resistant organisms. They address the complexities of treatment regimens, particularly in cases of carbapenem-resistant infections. The document emphasizes the importance of considering the site of infection and the susceptibility of pathogens when deciding on therapy. It aims to guide clinicians in making informed decisions regarding polymyxin-based therapies.