INFECTIOUS DISEASES SOCIETY OF AMERICA GUIDANCE ON THE TREATMENT OF EXTENDED-SPECTRUM β-LACTAMASE PRODUCING ENTEROBACTERALES (ESBL-E), CARBAPENEM-RESISTANT ENTEROBACTERALES (CRE), AND PSEUDOMONAS AERUGINOSA WITH DIFFICULT-TO-TREAT RESISTANCE (DTR- P.

Johns Hopkins University School of Medicine, The University of Texas MD Anderson Cancer Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, University Hospitals Cleveland Medical Center, University of Virginia, University of

Antimicrobial-resistant infections are commonly encountered in US hospitals and result in significant morbidity and mortality. A panel of six infectious diseases specialists formulated common questions regarding the treatment of ESBL-E, CRE, and DTR-P. aeruginosa. The document outlines preferred antibiotic therapies and management strategies for these challenging infections.