GOUT

Rheumatology

Gout is characterized by the deposition of monosodium urate monohydrate crystals in joints and surrounding tissues, leading to inflammation and pain. The document outlines the prevalence of gout, which is more common in males and increases with age and obesity. It discusses the pathophysiological mechanisms behind hyperuricemia and crystal formation, as well as the clinical presentation of gout flares and the phases of the disease. Diagnostic criteria and management options, including pharmacological treatments and lifestyle modifications, are also detailed.