EAU Guidelines 2023

N. Mottet

These guidelines, developed by a consortium of European medical societies, provide a detailed overview of prostate cancer management. They address the aetiology and risk factors, including hereditary components and lifestyle influences. The document outlines current classification and staging systems, emphasizing the Gleason score and ISUP grade. Diagnostic evaluation strategies, such as screening, early detection methods, and genetic testing, are discussed, alongside clinical diagnostic tools like DRE and PSA. The guidelines also delve into treatment strategies for advanced disease, including considerations for changing treatment in mCRPC based on progression criteria and clinical benefit.