Comprehensive Care for Sickle Cell Disease by Dr Ruth Namazzi 1 (2)

Makerere University College of Health Sciences

The document outlines the burden of sickle cell disease in sub‑Saharan Africa and Uganda, describing its genetic basis and clinical manifestations. It presents a framework for comprehensive care across the lifespan, including preventive measures such as immunisation, penicillin, and malaria prophylaxis. Detailed protocols for hospital management of vaso‑occlusive pain crises are provided, highlighting pain assessment, analgesic dosing, and adjunctive therapies. The module also discusses hydroxyurea dosing, monitoring, and challenges, as well as fertility considerations for patients on therapy.