BETA-BLOCKERS FOR THE TREATMENT OF ARRHYTHMIAS: WHICH DRUG FOR WHICH ARRHYTHMIA?

Lucian Muresan, Gabriel Cismaru, Stefan Lucian Popa, Radu Rosu, Gabriel Gusetu, Mihai Puiu, Razvan Olimpiu Mada, Crina Muresan, Ronan Le Bouar, Serban Schiau, Charline Daval, Jacques Levy, Raphael Pedro Martins

Beta-blockers are widely used in managing both supraventricular and ventricular arrhythmias, yet they are not a homogeneous class of drugs. This review highlights the differences in beta1-receptor selectivity, lipophilicity, half-life, and other properties among beta-blockers, and how these differences impact their efficacy in treating specific arrhythmias. The evidence is drawn from a comprehensive search of multiple databases, prioritizing randomized controlled trials and contemporary guidelines, and is synthesized qualitatively by arrhythmia type.