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Clinical reviews
AUTOINFLAMMATORY SYNDROMES OF HIDRADENITIS SUPPURATIVA: UPDATES IN CLINICAL FEATURES, EMERGING ASSOCIATIONS, AND MANAGEMENT
Jade Y. Ho, Andrew L. Liang, Carlo Alberto Maronese, Angelo Valerio Marzano, John M. Davis, Vincent Piguet, Afsaneh Alavi
PDF202611 pages888 KB
Hidradenitis suppurativa (HS) is associated with various autoinflammatory syndromes, which have traditionally included conditions like pyoderma gangrenosum and acne. Recent literature suggests an expanding spectrum of these syndromes, driven by dysregulation of the innate immune system and the overexpression of inflammatory cytokines. The document discusses recent findings on treatment responses to biologics targeting IL-1 and IL-17, as well as genetic factors implicated in these syndromes.
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