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Clinical reviews
ANGIOTENSIN RECEPTOR-NEPRILYSIN INHIBITORS FOR KIDNEY PROTECTION IN HEART FAILURE
Pontifical Javeriana University
PDF20262 pages237 KB
The article reviews recent findings on the use of sacubitril/valsartan, an angiotensin receptor-neprilysin inhibitor, and its effects on renal outcomes in heart failure patients. It highlights secondary analyses from landmark heart failure trials that suggest potential renal benefits, including reduced rates of eGFR decline and favorable signals on renal endpoints. The discussion emphasizes the importance of integrating these findings into guideline-directed medical therapy for chronic kidney disease, regardless of heart failure status.
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