ammenorrhea 3

Osler Clinical Library

The document defines amenorrhea and distinguishes primary from secondary forms, outlining physiological states such as pre‑puberty, pregnancy, and lactation. It details pathological causes including genital outflow tract anomalies, ovarian, pituitary, and hypothalamic disorders. Hormonal evaluation strategies, especially serum FSH and estradiol interpretation, are described. Management approaches for conditions like PCOS, hyperprolactinemia, and gonadal dysgenesis are presented, including hormonal contraceptives, metformin, and fertility interventions.