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American College of Gastroenterology
Celiac Disease (CD) is characterized by a permanent immune-mediated response to gluten, leading to small bowel injury and various clinical manifestations. This document outlines the diagnostic criteria, including the importance of serological tests and intestinal biopsy, and discusses treatment strategies, primarily focusing on a strict gluten-free diet. It also addresses the challenges of nonresponsive and refractory CD, emphasizing the need for systematic workups in such cases.
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