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American College of Gastroenterology
Celiac disease (CD) is defined as a permanent immune-mediated response to gluten present in wheat, barley, and rye, characterized by small bowel injury and specific antibodies. The guideline discusses the importance of serological tests for initial screening and the necessity of intestinal biopsy for diagnosis confirmation. It also outlines the current treatment, which involves strict adherence to a gluten-free diet (GFD) and the management of nonresponsive and refractory CD cases.
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