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Clinical reviews
ESC 2024 Hypertension Guidelines
College
·
General Medicine
· 2024
· 40 pages
The 2024 ESC Guidelines for the management of elevated blood pressure and hypertension represent an important update, incorporating emerging evidence on blood pressure targets, risk stratification, and patient-centered care approaches. This document emphasizes a shift from binary classification to a continuum model of blood pressure and cardiovascular risk.
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Clinical reviews
BEYOND DYSPEPSIA: PREVENTING THE COMPLICATIONS OF HELICOBACTER PYLORI INFECTION
Dr. Anthony Ocanit
·
Gastroenterology
· 2026
· 17 pages
This document discusses the burden of Helicobacter pylori infection, its pathogenesis, clinical presentations, and the importance of testing and treatment to prevent complications.
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Clinical reviews
Management of Hypertension in Diabetic Kidney Disease
European Society of Cardiology
·
Cardiology
· 2024
· 40 pages
This clinical review outlines the therapeutic framework for managing hypertension in patients with diabetic kidney disease, focusing on blood pressure targets, renin-angiotensin-aldosterone system (RAAS) blockade, and organ-protective pharmacotherapy.
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Clinical reviews
Acute Hypoxemic Respiratory Failure
Warren Isakow, M.D.
·
Critical Care
· 18 pages
An overview of acute respiratory failure, defining the condition, classifying it into hypoxemic and hypercapnic types, and outlining the underlying pathophysiology and clinical approach to diagnosis and management.
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Clinical reviews
Acute Respiratory Failure Overview
Warren Isakow, M.D.
·
Critical Care Medicine
· 2007
· 1 pages
An overview of acute respiratory failure, describing its classification into hypoxemic and hypercapnic types, underlying pathophysiology, and a stepwise diagnostic approach.
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Clinical reviews
Persistent Critical Illness in COVID-19: A Scottish Cohort Study
University of Edinburgh, Public Health Scotland, NHS Forth Valley, NHS Grampian, NHS Greater Glasgow and Clyde, University of Glasgow, NHS Lothian
·
Critical Care
· 2022
· 10 pages
This study examines the prevalence, risk factors, and long-term outcomes of critically ill patients with COVID-19 and persistent critical illness in Scotland. Almost half of all patients with COVID-19 admitted to critical care developed persistent critical illness, with high resource use in critical care and beyond.
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Clinical reviews
Epilepsy Risk After Febrile Convulsions
Addenbrooke's Hospital, Cambridge
·
Pediatrics
· 1991
· 4 pages
A national cohort study to identify children with febrile brain damage and determine the number and type of subsequent afebrile seizures. The study found that the risk of epilepsy after febrile convulsions is higher for children with complex febrile convulsions.
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Clinical reviews
Nursing Students' Clinical Practice Experiences: A Qualitative Study
Shiraz University of Medical Sciences, Iran
·
Nursing Education
· 2005
· 7 pages
A qualitative focus‑group study of 90 nursing students at Shiraz University of Medical Sciences identified themes such as initial clinical anxiety, theory‑practice gap, clinical supervision, and professional role, revealing dissatisfaction and anxiety about clinical competence.
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Clinical reviews
Chamberlain's Symptoms and Signs in Clinical Medicine
The Third People's Hospital of Shanghai Second Medical College
·
Internal Medicine
· 1980
· 1 pages
A classic introductory guide to medical diagnosis, covering history taking, general principles of examination, case recording, and the symptoms and signs of various organ systems, including dedicated chapters on fever, tropical medicine, and pediatric examination.
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Clinical reviews
2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department
Department of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara
·
Emergency Medicine
· 2023
· 23 pages
This review aims to update physicians on the main pillars of treatment for sepsis and septic shock, including empirical antimicrobial treatment, fluid replacement, and vasoactive agents. The management of sepsis and septic shock has significantly progressed in the last few years, and improving knowledge of the main therapeutic cornerstones is crucial to achieve better patient outcomes.
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Clinical reviews
2025 ADA Diabetes Care Standards Updates
American Diabetes Association
·
Endocrinology
· 2025
· 11 pages
A concise overview of the 2025 ADA Standards of Care updates, highlighting changes relevant to primary care practice such as terminology, weight‑based treatment, expanded CGM use, and new screening recommendations.
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Clinical reviews
ABC of intensive care
Hospital
·
Critical Care
· 1999
· 49 pages
This document reviews the history, organization, patient case mix, provision, and staffing of intensive care units, highlighting ongoing challenges related to costs, resource allocation, and admission criteria.
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Clinical reviews
Non-Tuberculous Mycobacteria Pulmonary Disease: A Review
University of the Witwatersrand, Johannesburg, South Africa; University Joseph KI-ZEBRO, Ouagadougou, Burkina Faso
·
Pulmonology
· 2022
· 5 pages
Non-tuberculous mycobacteria reports have been on the rise globally, with increasing incidence and prevalence accompanied by poor outcomes. This review highlights the rising incidence, important risk factors, diagnosis and management of NTM pulmonary disease.
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Clinical reviews
AOGU Position Statement on Acetaminophen Use in Pregnancy
Association of Obstetricians and Gynaecologists of Uganda (AOGU)
·
Obstetrics and Gynecology
· 2025
· 2 pages
Paracetamol (Acetaminophen) is recommended for treatment of fever and pain in pregnancy, despite recent media reports suggesting an association with autism spectrum disorder, as the quality of evidence supporting this claim is weak. AOGU reaffirms that Paracetamol should remain the first-line treatment for the management of pain and fever in pregnancy when medically indicated.
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Clinical reviews
Hypertension Risk Factors in Adolescent Students
Zhengzhou University, College of Public Health
·
Cardiology
· 2019
· 9 pages
This study investigates the prevalence of hypertension and its risk factors among adolescent Senior High School students in Ghana, with a focus on the need for early intervention and education.
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Clinical reviews
Abortion in Uganda
Ministry of Health (Uganda)
·
Obstetrics and Gynecology
· 5 pages
The article outlines Uganda's restrictive abortion laws, the resulting reliance on unsafe abortions, and the associated maternal mortality and family planning challenges.
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Clinical reviews
Abruption Placentae: Diagnosis and Approach to Management
KNRH
·
Obstetrics and Gynecology
· 31 pages
An overview of placental abruption covering definition, risk factors, clinical presentation, diagnostic methods, and maternal‑fetal complications with recommended management strategies.
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Clinical reviews
Prevalence and Factors Associated with Anaemia in Namutumba District, Uganda
Makerere University School of Public Health
·
Pediatrics
· 2017
· 9 pages
This study assessed the prevalence and factors associated with anaemia among children aged 6 to 59 months in Namutumba district, Uganda, and found a high prevalence of anaemia, especially among children in rural areas.
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Clinical reviews
7 vs 14 Days Antibiotic Treatment for Bloodstream Infections
University of Toronto, Sunnybrook Health Sciences Centre
·
Infectious Diseases
· 2024
· 14 pages
A multicenter, noninferiority trial comparing 7-day and 14-day antibiotic treatment durations in hospitalized patients with bloodstream infections, finding that 7-day treatment was noninferior to 14-day treatment.
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Clinical reviews
A Systematic Approach to Patients with Jaundice
University of Chicago Medicine
·
Gastroenterology
· 2016
· 6 pages
This review discusses the mechanisms of cholestasis and jaundice and outlines a stepwise diagnostic approach using laboratory tests and imaging to evaluate patients with hyperbilirubinemia.
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Clinical reviews
Connective Tissue Disease-Associated Interstitial Lung Disease: A Rheumatologist’s Perspective
Beaumont Hospital, Dublin, Ireland
·
Rheumatology
· 2025
· 9 pages
Pulmonary manifestations are common and are among the leading causes of death for patients with rheumatic diseases; immunosuppressive therapies can be effective for CTD‑ILD, and screening high‑risk patients allows earlier intervention.
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Clinical reviews
Emergencies in HIV Disease
Kiruddu National Referral Hospital
·
Infectious Diseases
· 2024
· 42 pages
A review of inpatient HIV mortality in Uganda, presenting data from Kiruddu National Referral Hospital (2020‑2023) and highlighting the high mortality rate, prevalence of advanced HIV disease, and key predictors of death.
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Clinical reviews
Cell Biology of Candida albicans and Host Interactions
University of Aberdeen
·
Infectious Diseases
· 2016
· 8 pages
This review summarizes recent advances in the cell biology of Candida albicans, focusing on its dual commensal and pathogenic states, host interactions, and mechanisms of adaptation such as phenotypic switching and the gastrointestinal (GUT) phenotype.
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Clinical reviews
Pharmacological Therapy for Stable COPD
China‑Japan Friendship Hospital, Beijing, China
·
Pulmonology
· 2023
· 8 pages
This review summarizes pharmacological therapies for stable chronic obstructive pulmonary disease (COPD), discussing bronchodilators, inhaled corticosteroids, and combination regimens, and highlights the need for individualized treatment and further clinical trials.
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