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Clinical reviews
THE SUPPLEMENTAL NUTRITION ASSISTANCE PROGRAM
College of Nursing, University of Acadia
·
Public Health
· 2025
· 15 pages
This document critically analyzes the implications of the One Big Beautiful Bill Act (OBBBA) on the Supplemental Nutrition Assistance Program (SNAP), focusing on its effects on maternal and child health.
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Clinical reviews
NATIONAL MORTALITY SURVEILLANCE BULLETIN APRIL-JUNE 2025
Dr. Allan Muruta
·
Public Health
· 2025
· 6 pages
This bulletin shares mortality surveillance statistics in Uganda, aiming to identify the causes and demographics of deaths to inform public health responses.
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Clinical reviews
MANAGEMENT OF HYPERPHOSPHATEMIA IN ADULTS WITH CHRONIC KIDNEY DISEASE
UpToDate
·
Nephrology
· 2026
· 30 pages
This document reviews recommendations regarding target serum phosphorus concentration and treatment options for hyperphosphatemia in patients with chronic kidney disease (CKD).
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Clinical reviews
BLOOD GLUCOSE TRAJECTORIES IN DIABETES PATIENTS RECEIVING CAPDCA MODEL OF PERSONALISED PATIENT EDUCATION: A CLUSTER RANDOMISED CONTROLLED TRIAL
Hospital, Capital Medical University, Beijing, China
·
Endocrinology
· 2025
· 9 pages
This study evaluates the efficacy of the CAPDCA model of structured and individualised health education in managing diabetes. It compares outcomes between an intervention group receiving this education and a control group receiving traditional education.
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Clinical reviews
DIAGNOSING DIABETIC NEUROPATHY: SOMETHING OLD, SOMETHING NEW
Division of Research, Weill Cornell Medicine Qatar, Doha, Qatar
·
Neurology
· 2018
· 15 pages
This document reviews the various methods for assessing diabetic peripheral neuropathy (DPN) and highlights the need for reliable biomarkers to facilitate drug discovery in DPN.
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Clinical reviews
DRUG ADMINISTRATION AND PRESCRIBING AUDIT REPORT
St. Francis Naggalama Hospital
·
Pharmacy
· 2026
· 3 pages
This report presents the findings of an audit conducted by the Drug and Therapeutics Committee on prescribing practices requiring pharmacy intervention. It identifies discrepancies in prescriptions and offers recommendations to enhance medication safety and prescribing efficiency.
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Clinical reviews
Desimone Et Al 2026 Infective Endocarditis Diagnosis Antibiotic
American Heart Association
·
Cardiology
· 27 pages
This scientific statement from the American Heart Association provides an updated overview of infective endocarditis, covering recent changes in incidence, epidemiology, diagnostic methods, and treatment options. It emphasizes the evolving landscape of diagnosis and management, including novel techniques and the importance of multidisciplinary teams.
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Clinical reviews
LDL CHOLESTEROL LOWERING WITH EVOLOCUMAB BEFORE PERCUTANEOUS CORONARY INTERVENTION FOR ACUTE MYOCARDIAL INFARCTION
AMUNDSEN Investigators of the ACTION Study Group
·
Cardiology
· 2026
· 9 pages
This study investigates the effects of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibition using evolocumab on LDL cholesterol levels in patients undergoing percutaneous coronary intervention for acute myocardial infarction.
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Clinical reviews
CLINICAL AND BACTERIOLOGICAL EFFECTIVENESS OF THREE DIFFERENT SHORT-COURSE ANTIBIOTIC REGIMENS AND SINGLE-DOSE FOSFOMYCIN FOR UNCOMPLICATED LOWER URINARY TRACT INFECTIONS IN WOMEN (SCOUT): A PRAGMATIC, MULTICENTRE, OPEN-LABEL, RANDOMISED CLINICAL TRIAL
Carl Llor, Ramon Monfà, Ana Garcia-Sangenís, Alfonso Leiva, Jaime Marín-Cañada, María Antonia Sánchez-Calavera, Ana Moragas, Mercedes Aguilar-Sánchez, Amelia Troncoso-Mariño, Ricardo Rodríguez-Barrientos, José M Molero, Dan Ouchi, Cristina
·
Urology
· 2024
· 11 pages
This study evaluates the effectiveness and safety of a single dose of fosfomycin compared with two doses of fosfomycin and short-course regimens of nitrofurantoin and pivmecillinam in women with urinary tract infection symptoms.
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Clinical reviews
INTEGRATED MANAGEMENT STRATEGIES FOR HYPERTENSION AND DIABETES IN CARDIOVASCULAR
Department of Cardiology, Rama Medical College and Hospital; Santosh Cardiac Care Centre; PCET’s Pimpri Chinchwad University; Dr. N. D. Desai Faculty of Medical Science and Research; Smt. B. K. Shah Medical Institute and Research Centre; National Medical
·
Cardiology
· 2026
· 12 pages
This open access review article discusses the interconnectedness of type 2 diabetes and hypertension, emphasizing the need for integrated management strategies to mitigate cardiovascular risks.
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Clinical reviews
EFFICACIES OF ARTEMETHER–LUMEFANTRINE, ARTESUNATE–AMODIAQUINE, DIHYDROARTEMISININ–PIPERAPQUINE, AND ARTESUNATE–PYRONARIDINE FOR THE TREATMENT OF UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA IN CHILDREN AGED 6 MONTHS TO 10 YEARS IN UGANDA: A RANDOMISED,
Authority
·
Infectious Disease
· 2025
· 12 pages
This clinical trial evaluates the efficacy of various artemisinin-based combination therapies for treating uncomplicated Plasmodium falciparum malaria in Ugandan children aged 6 months to 10 years.
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Clinical reviews
TRANSCATHETER AORTIC VALVE REPLACEMENT OR MEDICAL TREATMENT FOR PARADOXICAL LOW-FLOW, LOW-GRADIENT AORTIC VALVE STENOSIS
American College of Cardiology Foundation
·
Cardiology
· 2026
· 16 pages
This study investigates the efficacy of transcatheter aortic valve replacement (TAVR) compared to optimal medical therapy (OMT) in patients with paradoxical low-flow, low-gradient aortic stenosis.
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Clinical reviews
ANTICOAGULATION MONOTHERAPY VS ANTIPLATELET MONOTHERAPY AFTER TRANSCATHETER AORTIC VALVE IMPLANT
JAMA
·
Cardiology
· 2026
· 10 pages
This study evaluates the safety and efficacy of a factor Xa inhibitor non–vitamin K antagonist oral anticoagulant (NOAC) monotherapy strategy compared to an acetylsalicylic acid (ASA) monotherapy strategy after transcatheter aortic valve implant (TAVI).
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Clinical reviews
AFICAMTEN FOR SYMPTOMATIC NONOBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY
ACACIA-HCM Investigators
·
Cardiology
· 2026
· 12 pages
This article discusses the efficacy and safety of aficamten, a cardiac myosin inhibitor, in patients with symptomatic nonobstructive hypertrophic cardiomyopathy (HCM). It presents findings from a phase 3, multinational, double-blind trial.
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Clinical reviews
OVERLAP OF DIABETIC KETOACIDOSIS AND HYPEROSMOLAR HYPERGLYCEMIC STATE
Texas A&M University Health Science Center
·
Critical Care
· 2022
· 11 pages
This document reviews the clinical overlap between diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS), focusing on their pathophysiology, diagnosis, and management strategies.
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Clinical reviews
THE IMPACT OF EARLY CRYOBALLOON ABLATION ON CLINICAL OUTCOMES IN PATIENTS WITH NON-PAROXYSMAL ATRIAL FIBRILLATION
Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, the Second Hospital of Tianjin Medical University, Tianjin, China; School of Nursing and Health Sciences, Hong Kong
·
Cardiology
· 2025
· 8 pages
This study examines the impact of early cryoballoon ablation on atrial fibrillation recurrence in patients diagnosed with non-paroxysmal atrial fibrillation.
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Clinical reviews
TIMING OF PCI IN PATIENTS UNDERGOING TRANSCATHETER AORTIC-VALVE IMPLANTATION
B.E. Stähli, F. Ruschitzka, D. Westermann, A. Linke, N. Mangner, N.M. Van Mieghem, R. Kesterke, L. Oberholzer, J. Rothe, C. von zur Mühlen, T. Zeus, W.-K. Kim, P. Lauten, N. Werner, C. Burgdorf, H. Alber, P.C. Schulze, M. Joner, J. Michel, A. Candreva,
·
Cardiology
· 13 pages
This article investigates the timing of percutaneous coronary intervention (PCI) in patients undergoing transcatheter aortic-valve implantation (TAVI), focusing on the optimal treatment strategy for patients with concomitant coronary artery disease.
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Clinical reviews
RACIAL DIFFERENCES IN ATRIAL FIBRILLATION MANAGEMENT BETWEEN WHITE PATIENTS AND BLACK PATIENTS IN TRANSTHYRETIN CARDIAC AMYLOID
Lindsey R. Mitrani, MD; Robert A. Tumasian, III, BS; Silvia Vilches, MD; Jeffeny De Los Santos, MD, MHA; Esther Gonzalez-Lopez, MD; Angelo Giuseppe Caponetti, MD; Giulia Saturi, MD; Jesus G. Mirelis, MD; Simone Longhi, MD; Christian Gagliardi, MD; Jeff
·
Cardiology
· 7 pages
This study investigates the differences in atrial fibrillation (AF) management between White and Black patients with transthyretin cardiac amyloidosis (ATTR-CA), highlighting disparities in diagnosis and outcomes.
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Clinical reviews
EPLONTERSEN FOR TRANSTHYRETIN AMYLOID CARDIOMYOPATHY
CARDIO-TTRansform Investigators
·
Cardiology
· 2024
· 12 pages
This article discusses the effects of eplontersen, an antisense oligonucleotide, on transthyretin amyloidosis with cardiomyopathy (ATTR-CM), a progressive disease caused by the deposition of misfolded transthyretin.
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Clinical reviews
CLOPIDOGREL OR DUAL ANTIPLATELET THERAPY IN HIGH-ISCHEMIC-RISK PATIENTS
Severance Hospital, Yonsei University
·
Cardiology
· 2026
· 12 pages
This article examines the effects of clopidogrel monotherapy compared to extended dual antiplatelet therapy with clopidogrel and aspirin in patients at high risk for recurrent ischemic events after drug-eluting stent implantation.
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Clinical reviews
GLOBAL PREVALENCE AND CHARACTERISTICS OF INFECTIONS AND CLINICAL OUTCOMES IN HOSPITALISED PATIENTS WITH CIRRHOSIS: A PROSPECTIVE COHORT STUDY FOR THE CLEARED CONSORTIUM
CLEARED Consortium
·
Gastroenterology
· 2024
· 13 pages
This study investigates the prevalence of infections and their clinical outcomes in hospitalized patients with cirrhosis across various regions. It aims to highlight regional variations and associations with clinical outcomes.
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Clinical reviews
COFFEE AND TEA INTAKE, DEMENTIA RISK, AND COGNITIVE FUNCTION
Yu Zhang, MBBS; Yuxi Liu, PhD; Yanping Li, PhD; Yuhan Li, MS; Xiao Gu, PhD; Jae H. Kang, ScD; A. Heather Eliassen, ScD; Molin Wang, PhD; Eric B. Rimm, ScD; Walter C. Willett, MD, DrPH; Frank B. Hu, MD, PhD; Meir J. Stampfer, MD, DrPH; Dong D. Wang, MD,
·
Neurology
· 2025
· 14 pages
This study investigates the associations between coffee and tea intake with dementia risk and cognitive function, utilizing data from large prospective cohort studies.
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Clinical reviews
THE NATIONAL PSORIASIS FOUNDATION PRIMER ON GLP-1 RECEPTOR AGONISTS IN PSORIASIS
National Psoriasis Foundation
·
Dermatology
· 11 pages
This document reviews the potential role of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in the treatment of psoriasis, highlighting their immune modulation effects and implications for managing comorbidities associated with the disease.
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Clinical reviews
COMPLETE REVASCULARIZATION GUIDED BY FUNCTIONAL CORONARY ANGIOGRAPHY IN STEMI
Azienda Ospedaliera Universitaria S. Anna, Cona, Italy
·
Cardiology
· 2026
· 10 pages
This original article discusses the recommended strategy for complete coronary-artery revascularization in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease, comparing functional coronary angiography with conventional angiography.
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