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Clinical reviews
INTERSTITIAL LUNG DISEASE IN 2025—PROGRESS, CHALLENGES, AND HOPE AHEAD
Department of Pulmonary Medicine, Integrated Hospital Institute, Cleveland Clinic, Cleveland, OH, USA
·
Pulmonology
· 2025
· 2 pages
This editorial discusses the challenges and advancements in the management of interstitial lung disease (ILD), highlighting the need for personalized approaches to care.
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Clinical reviews
WHAT MAKES A META-ANALYSIS BELIEVABLE?
Cedars-Sinai Medical Center, Yale School of Medicine, University of Glasgow
·
Cardiology
· 2026
· 4 pages
This document discusses the credibility of meta-analyses, highlighting their influence on clinical practice and the importance of methodological rigor. It addresses the risks of overinterpretation and the necessity for a thorough risk-of-bias assessment.
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Clinical reviews
ABDOMINAL PAIN IN THE EMERGENCY DEPARTMENT
Ochsner Medical Center, University of North Carolina at Chapel Hill
·
Emergency Medicine
· 15 pages
This document discusses the common missed diagnoses associated with abdominal pain in the emergency department, emphasizing the importance of thorough clinical assessments and follow-up plans.
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Clinical reviews
ACETAZOLAMIDE AS A DECONGESTION STRATEGY IN ACUTE DECOMPENSATED HEART FAILURE: BALANCING FLUID REMOVAL AND ELECTROLYTE DISTURBANCES
Kaiser Permanente San Francisco Medical Center
·
Cardiology
· 10 pages
This document discusses the use of acetazolamide as an adjunctive therapy for decongestion in patients with acute decompensated heart failure (ADHF), focusing on balancing fluid removal and electrolyte disturbances.
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Clinical reviews
DYS LIPIDEMIA
Johns Hopkins University School of Medicine, Baltimore
·
Cardiology
· 2023
· 17 pages
Dyslipidemia is an important risk factor for coronary artery disease and stroke, necessitating lifestyle interventions and lipid-lowering therapy for at-risk individuals.
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Clinical reviews
PANCREATIC SENESCENCE AND ITS CLINICAL MANIFESTATIONS
Huadong Hospital Affiliated to Fudan University, Shanghai, China
·
Gastroenterology
· 2020
· 5 pages
This article reviews the manifestations of pancreatic senescence and its significance for clinical practice, highlighting the changes in pancreatic structure and function with aging.
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Clinical reviews
PROGRESS AND CHALLENGES IN BACTERIAL MENINGITIS
Rodrigo Hasbun, MD, MPH
·
Infectious Disease
· 2022
· 8 pages
This review discusses the global health problem of bacterial meningitis, highlighting its incidence, mortality rates, and the common pathogens involved. It also addresses risk factors, symptoms, and the importance of timely diagnosis and treatment.
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Clinical reviews
PREGNANCY IN CHRONIC KIDNEY DISEASE
Yale University School of Medicine
·
Nephrology
· 2023
· 10 pages
This document discusses the management of chronic kidney disease (CKD) and acute kidney injury in pregnant women, highlighting the complexities and multidisciplinary approaches required for effective care.
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Clinical reviews
THE NEW IN ANTICOAGULATION: FACTOR XI INHIBITORS
Floraspe-Renzetti Hospital, ASL Lanciano-Vasto-Chieti; University of Pisa
·
Cardiology
· 2023
· 4 pages
This document discusses the emerging role of factor XI inhibitors in anticoagulation therapy, highlighting their potential to reduce thrombotic risk with minimal bleeding complications. It reviews various pharmacological strategies currently under investigation.
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Clinical reviews
RISK FOR BLEEDING-RELATED HOSPITALIZATIONS DURING USE OF AMIODARONE WITH APIXABAN OR RIVAROXABAN IN PATIENTS WITH ATRIAL FIBRILLATION
Annals of Internal Medicine
·
Cardiology
· 2023
· 11 pages
This study investigates the risk of bleeding-related hospitalizations in patients with atrial fibrillation receiving amiodarone alongside apixaban or rivaroxaban.
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Clinical reviews
CARDIOPROTECTION IN PATIENTS AT HIGH RISK OF ANTHRACYCLINE-INDUCED CARDIOTOXICITY
American College of Cardiology Foundation
·
Cardiology
· 2023
· 6 pages
This primer focuses on the evidence for cardioprotection strategies to mitigate anthracycline-related cardiotoxicity in high-risk patients. It discusses the potential for myocardial injury and heart failure associated with anthracycline treatment.
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Clinical reviews
MODULATION AND PERSONALIZATION OF THERAPY AFTER ACUTE CORONARY SYNDROMES: THE ROAD TO PRECISION
Heart Institute and Sorbonne University, National College of French Cardiologists, Sapienza University of Rome, Medical University of Lodz, Universita Cattolica de Sacro Cuore
·
Cardiology
· 2023
· 3 pages
This document discusses the importance of modulating and personalizing therapy for patients after acute coronary syndromes (ACS) to improve outcomes. It highlights the need for tailored treatment strategies that consider individual patient characteristics.
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Clinical reviews
H. PYLORI INFECTION: COMMON QUESTIONS AND ANSWERS
The Ohio State University Wexner Medical Center
·
Gastroenterology
· 8 pages
This document addresses common questions regarding peptic ulcer disease and its association with Helicobacter pylori infection, including treatment strategies and management recommendations.
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Clinical reviews
CLASSIFYING ENTERAL NUTRITION: TAILORED FOR CLINICAL PRACTICE
Springer Science+Business Media, LLC
·
Nutrition
· 2019
· 7 pages
This document discusses the different forms of enteral nutrition and outlines the available evidence for its use in specific conditions, highlighting how enteral nutrition composition may influence relevant outcomes.
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Clinical reviews
CIRRHOTIC COAGULOPATHY: A REBALANCED HEMOSTASIS
Cleveland Clinic, Case Western Reserve University
·
Gastroenterology
· 11 pages
This review discusses the complexities of coagulation in patients with cirrhosis, challenging the traditional view of cirrhosis as a hypocoagulable state. It highlights the simultaneous decrease in both clotting and anticlotting factors, leading to a new equilibrium in hemostasis.
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Clinical reviews
SACUBITRIL/VALSARTAN IN THE TREATMENT OF RESISTANT HYPERTENSION: RAISING STAR OR ILLUSION?
Klinik für Innere Medizin II, Cardiology Department, Universitätsklinikum Ulm; Department of Medicine and Surgery, University of Milano-Bicocca
·
Cardiology
· 3 pages
This editorial discusses the efficacy of sacubitril/valsartan in treating resistant hypertension, highlighting its potential benefits and limitations based on recent studies.
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Clinical reviews
OPTIMAL DIURETIC STRATEGIES IN HEART FAILURE
University of Alabama at Birmingham
·
Cardiology
· 2021
· 8 pages
This review article discusses the optimal diuretic strategies for managing heart failure, focusing on the implications of various diuretics and their effects on patient outcomes.
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Clinical reviews
EVALUATION OF HYDROCORTISONE, VITAMIN C, AND THIAMINE FOR THE TREATMENT OF SEPTIC SHOCK: A RANDOMIZED CONTROLLED TRIAL (THE HYVITS TRIAL)
Saint Luke’s Hospital of Kansas City; Hamad General Hospital, Hamad Medical Corporation; Weill Cornell Medicine-Qatar; Al Wakra Hospital, Hamad Medical Corporation; University of North Carolina Rex Hospital; Penn State Health Milton S. Hershey Medical
·
Critical Care Medicine
· 2023
· 5 pages
This study evaluates the effect of combined hydrocortisone, vitamin C, and thiamine on patients with septic shock in a randomized controlled trial format.
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Clinical reviews
HAEMODYNAMIC VALIDATION OF THE THREE-STEP HFA-PEFF ALGORITHM TO DIAGNOSE HEART FAILURE WITH PRESERVED EJECTION FRACTION
Department of Management, Information and Production Engineering, University of Bergamo; Department of Cardiology, Istituto Auxologico Italiano IRCCS; Department of Clinical Sciences and Community Health, University of Milan; Department of
·
Cardiology
· 2023
· 8 pages
This article presents the validation of the HFA-PEFF algorithm, a three-step approach for diagnosing heart failure with preserved ejection fraction (HFpEF). It evaluates the algorithm's effectiveness in determining the likelihood of HFpEF in patients.
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Clinical reviews
SURGICAL SITE INFECTION PREVENTION
null
·
Surgery
· 2022
· 9 pages
This document reviews the prevention strategies for surgical site infections, which affect a significant percentage of surgical patients and can lead to extended hospital stays.
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Clinical reviews
INDIRECT TREATMENT COMPARISON BETWEEN FIXED-DOSE-COMBINATIONS OF AMLODIPINE/LOSARTAN AND AMLODIPINE/VALSARTAN IN BLOOD PRESSURE CONTROL
A. Lawrence Gould, S. Unniachan, D. Wu
·
Cardiology
· 2013
· 10 pages
This study compared blood pressure changes after 8 weeks of therapy between a fixed-dose combination of amlodipine/losartan and amlodipine/valsartan using a network meta-analysis.
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Clinical reviews
EFFICIENCY OF NEBULIZING FUROSEMIDE IN THE TREATMENT OF CHRONIC PULMONARY OBSTRUCTIVE DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS OF CLINICAL TRIALS
Shahid Mostafa Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran
·
Pulmonology
· 2020
· 10 pages
This systematic review and meta-analysis investigates the therapeutic effects of nebulizing furosemide compared to placebo in patients with chronic obstructive pulmonary disease (COPD). The study aims to provide evidence on the efficacy of nebulized furosemide as a treatment option for COPD.
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Clinical reviews
SPHINCTER OF ODDI DYSFUNCTION: SPHINCTER OF ODDI DYSFUNCTION OR DISCORDANCE? WHAT IS THE STATE OF THE ART IN 2018?
Jong Jin Hyun, Richard A. Kozarek
·
Gastroenterology
· 2018
· 6 pages
This document reviews important manuscripts published over the previous two years related to sphincter of Oddi dysfunction (SOD), highlighting recent findings and treatment approaches.
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Clinical reviews
CELIAC DISEASE: WHO SHOULD I TEST, AND HOW?
Cleveland Clinic
·
Gastroenterology
· 4 pages
This document discusses the testing recommendations for celiac disease, particularly focusing on patients with chronic diarrhea or malabsorption. It outlines the symptoms and conditions associated with celiac disease and the appropriate screening tests.
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